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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke TK, Coleman JIR, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, Kiadeh FHF, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, Hickie IB, Hoffmann P, Homuth G, Horn C, Hottenga JJ, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi Y, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O'Reilly PF, Oskarsson H, Owen MJ, Painter JN, Pede… See abstract for full author list ➔ Wray NR, et al. Among authors: domenici e. Nat Genet. 2018 May;50(5):668-681. doi: 10.1038/s41588-018-0090-3. Epub 2018 Apr 26. Nat Genet. 2018. PMID: 29700475 Free PMC article.
Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts.
Muglia P, Tozzi F, Galwey NW, Francks C, Upmanyu R, Kong XQ, Antoniades A, Domenici E, Perry J, Rothen S, Vandeleur CL, Mooser V, Waeber G, Vollenweider P, Preisig M, Lucae S, Müller-Myhsok B, Holsboer F, Middleton LT, Roses AD. Muglia P, et al. Among authors: domenici e. Mol Psychiatry. 2010 Jun;15(6):589-601. doi: 10.1038/mp.2008.131. Epub 2008 Dec 23. Mol Psychiatry. 2010. PMID: 19107115
A follow-up case-control association study of tractable (druggable) genes in recurrent major depression.
Schosser A, Gaysina D, Cohen-Woods S, Domenici E, Perry J, Tozzi F, Korszun A, Gunasinghe C, Gray J, Jones L, Binder EB, Holsboer F, Craddock N, Owen MJ, Craig IW, Farmer AE, Muglia P, McGuffin P. Schosser A, et al. Among authors: domenici e. Am J Med Genet B Neuropsychiatr Genet. 2011 Sep;156B(6):640-50. doi: 10.1002/ajmg.b.31204. Epub 2011 May 31. Am J Med Genet B Neuropsychiatr Genet. 2011. PMID: 21630437
Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.
Tansey KE, Guipponi M, Perroud N, Bondolfi G, Domenici E, Evans D, Hall SK, Hauser J, Henigsberg N, Hu X, Jerman B, Maier W, Mors O, O'Donovan M, Peters TJ, Placentino A, Rietschel M, Souery D, Aitchison KJ, Craig I, Farmer A, Wendland JR, Malafosse A, Holmans P, Lewis G, Lewis CM, Stensbøl TB, Kapur S, McGuffin P, Uher R. Tansey KE, et al. Among authors: domenici e. PLoS Med. 2012;9(10):e1001326. doi: 10.1371/journal.pmed.1001326. Epub 2012 Oct 16. PLoS Med. 2012. PMID: 23091423 Free PMC article.
Contribution of common genetic variants to antidepressant response.
Tansey KE, Guipponi M, Hu X, Domenici E, Lewis G, Malafosse A, Wendland JR, Lewis CM, McGuffin P, Uher R. Tansey KE, et al. Among authors: domenici e. Biol Psychiatry. 2013 Apr 1;73(7):679-82. doi: 10.1016/j.biopsych.2012.10.030. Epub 2012 Dec 11. Biol Psychiatry. 2013. PMID: 23237317
Copy number variants and therapeutic response to antidepressant medication in major depressive disorder.
Tansey KE, Rucker JJ, Kavanagh DH, Guipponi M, Perroud N, Bondolfi G, Domenici E, Evans DM, Hauser J, Henigsberg N, Jerman B, Maier W, Mors O, O'Donovan M, Peters TJ, Placentino A, Rietschel M, Souery D, Aitchison KJ, Craig I, Farmer A, Wendland JR, Malafosse A, Lewis G, Kapur S, McGuffin P, Uher R. Tansey KE, et al. Among authors: domenici e. Pharmacogenomics J. 2014 Aug;14(4):395-9. doi: 10.1038/tpj.2013.51. Epub 2014 Jan 21. Pharmacogenomics J. 2014. PMID: 24445990
Biological insights from 108 schizophrenia-associated genetic loci.
Schizophrenia Working Group of the Psychiatric Genomics Consortium. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Nature. 2014 Jul 24;511(7510):421-7. doi: 10.1038/nature13595. Epub 2014 Jul 22. Nature. 2014. PMID: 25056061 Free PMC article.
145 results