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An ETFDH-driven metabolon supports OXPHOS efficiency in skeletal muscle by regulating coenzyme Q homeostasis.
Herrero Martín JC, Salegi Ansa B, Álvarez-Rivera G, Domínguez-Zorita S, Rodríguez-Pombo P, Pérez B, Calvo E, Paradela A, Miguez DG, Cifuentes A, Cuezva JM, Formentini L. Herrero Martín JC, et al. Among authors: dominguez zorita s. Nat Metab. 2024 Feb;6(2):209-225. doi: 10.1038/s42255-023-00956-y. Epub 2024 Jan 19. Nat Metab. 2024. PMID: 38243131 Free PMC article.
IF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype.
Domínguez-Zorita S, Romero-Carramiñana I, Santacatterina F, Esparza-Moltó PB, Simó C, Del-Arco A, Núñez de Arenas C, Saiz J, Barbas C, Cuezva JM. Domínguez-Zorita S, et al. Cell Death Dis. 2023 Jul 12;14(7):413. doi: 10.1038/s41419-023-05957-z. Cell Death Dis. 2023. PMID: 37433784 Free PMC article.
TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with TPL2 mRNA.
Escós A, Martín-Gómez J, González-Romero D, Díaz-Mora E, Francisco-Velilla R, Santiago C, Cuezva JM, Domínguez-Zorita S, Martínez-Salas E, Sonenberg N, Sanz-Ezquerro JJ, Jafarnejad SM, Cuenda A. Escós A, et al. Among authors: dominguez zorita s. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2204752119. doi: 10.1073/pnas.2204752119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994673 Free PMC article.
Analysis of the metabolic proteome of lung adenocarcinomas by reverse-phase protein arrays (RPPA) emphasizes mitochondria as targets for therapy.
Torresano L, Santacatterina F, Domínguez-Zorita S, Nuevo-Tapioles C, Núñez-Salgado A, Esparza-Moltó PB, González-Llorente L, Romero-Carramiñana I, Núñez de Arenas C, Sánchez-Garrido B, Nájera L, Salas C, Provencio M, Cuezva JM. Torresano L, et al. Among authors: dominguez zorita s. Oncogenesis. 2022 May 9;11(1):24. doi: 10.1038/s41389-022-00400-y. Oncogenesis. 2022. PMID: 35534478 Free PMC article.