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Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer.
Unterleuthner D, Neuhold P, Schwarz K, Janker L, Neuditschko B, Nivarthi H, Crncec I, Kramer N, Unger C, Hengstschläger M, Eferl R, Moriggl R, Sommergruber W, Gerner C, Dolznig H. Unterleuthner D, et al. Among authors: dolznig h. Angiogenesis. 2020 May;23(2):159-177. doi: 10.1007/s10456-019-09688-8. Epub 2019 Oct 30. Angiogenesis. 2020. PMID: 31667643 Free PMC article.
Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages.
Stadler M, Pudelko K, Biermeier A, Walterskirchen N, Gaigneaux A, Weindorfer C, Harrer N, Klett H, Hengstschläger M, Schüler J, Sommergruber W, Oehler R, Bergmann M, Letellier E, Dolznig H. Stadler M, et al. Among authors: dolznig h. Cancer Lett. 2021 Nov 1;520:184-200. doi: 10.1016/j.canlet.2021.07.006. Epub 2021 Jul 10. Cancer Lett. 2021. PMID: 34256095 Free article.
Metastatic colorectal carcinoma-associated fibroblasts have immunosuppressive properties related to increased IGFBP2 expression.
Walterskirchen N, Müller C, Ramos C, Zeindl S, Stang S, Herzog D, Sachet M, Schimek V, Unger L, Gerakopoulos V, Hengstschläger M, Bachleitner-Hofmann T, Bergmann M, Dolznig H, Oehler R. Walterskirchen N, et al. Among authors: dolznig h. Cancer Lett. 2022 Aug 1;540:215737. doi: 10.1016/j.canlet.2022.215737. Epub 2022 May 13. Cancer Lett. 2022. PMID: 35569697 Free article.
IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer.
Koncina E, Nurmik M, Pozdeev VI, Gilson C, Tsenkova M, Begaj R, Stang S, Gaigneaux A, Weindorfer C, Rodriguez F, Schmoetten M, Klein E, Karta J, Atanasova VS, Grzyb K, Ullmann P, Halder R, Hengstschläger M, Graas J, Augendre V, Karapetyan YE, Kerger L, Zuegel N, Skupin A, Haan S, Meiser J, Dolznig H, Letellier E. Koncina E, et al. Among authors: dolznig h. Nat Commun. 2023 Jul 17;14(1):4251. doi: 10.1038/s41467-023-39953-w. Nat Commun. 2023. PMID: 37460545 Free PMC article.
Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling.
Stadler S, Nguyen CH, Schachner H, Milovanovic D, Holzner S, Brenner S, Eichsteininger J, Stadler M, Senfter D, Krenn L, Schmidt WM, Huttary N, Krieger S, Koperek O, Bago-Horvath Z, Brendel KA, Marian B, de Wever O, Mader RM, Giessrigl B, Jäger W, Dolznig H, Krupitza G. Stadler S, et al. Among authors: dolznig h. Cell Mol Life Sci. 2017 May;74(10):1907-1921. doi: 10.1007/s00018-016-2441-5. Epub 2016 Dec 24. Cell Mol Life Sci. 2017. PMID: 28013338 Free PMC article.
Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression.
Kramer N, Schmöllerl J, Unger C, Nivarthi H, Rudisch A, Unterleuthner D, Scherzer M, Riedl A, Artaker M, Crncec I, Lenhardt D, Schwarz T, Prieler B, Han X, Hengstschläger M, Schüler J, Eferl R, Moriggl R, Sommergruber W, Dolznig H. Kramer N, et al. Among authors: dolznig h. Oncogene. 2017 Sep 28;36(39):5460-5472. doi: 10.1038/onc.2017.144. Epub 2017 May 29. Oncogene. 2017. PMID: 28553956
95 results