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From pyridinium-based to centrally active acetylcholinesterase reactivators.
Korabecny J, Soukup O, Dolezal R, Spilovska K, Nepovimova E, Andrs M, Nguyen TD, Jun D, Musilek K, Kucerova-Chlupacova M, Kuca K. Korabecny J, et al. Among authors: dolezal r. Mini Rev Med Chem. 2014;14(3):215-21. doi: 10.2174/1389557514666140219103138. Mini Rev Med Chem. 2014. PMID: 24552265 Review.
7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.
Korabecny J, Dolezal R, Cabelova P, Horova A, Hruba E, Ricny J, Sedlacek L, Nepovimova E, Spilovska K, Andrs M, Musilek K, Opletalova V, Sepsova V, Ripova D, Kuca K. Korabecny J, et al. Among authors: dolezal r. Eur J Med Chem. 2014 Jul 23;82:426-38. doi: 10.1016/j.ejmech.2014.05.066. Epub 2014 May 27. Eur J Med Chem. 2014. PMID: 24929293
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.
Nepovimova E, Korabecny J, Dolezal R, Babkova K, Ondrejicek A, Jun D, Sepsova V, Horova A, Hrabinova M, Soukup O, Bukum N, Jost P, Muckova L, Kassa J, Malinak D, Andrs M, Kuca K. Nepovimova E, et al. Among authors: dolezal r. J Med Chem. 2015 Nov 25;58(22):8985-9003. doi: 10.1021/acs.jmedchem.5b01325. Epub 2015 Nov 10. J Med Chem. 2015. PMID: 26503905
77 results