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Peptidomimetics in cancer targeting.
Gomari MM, Abkhiz S, Pour TG, Lotfi E, Rostami N, Monfared FN, Ghobari B, Mosavi M, Alipour B, Dokholyan NV. Gomari MM, et al. Among authors: dokholyan nv. Mol Med. 2022 Dec 7;28(1):146. doi: 10.1186/s10020-022-00577-3. Mol Med. 2022. PMID: 36476230 Free PMC article. Review.
ASR490, a Small Molecule, Overrides Aberrant Expression of Notch1 in Colorectal Cancer.
Tyagi A, Chandrasekaran B, Kolluru V, Baby BV, Sripathi CA, Ankem MK, Ramisetti SR, Chirasani VR, Dokholyan NV, Sharma AK, Damodaran C. Tyagi A, et al. Among authors: dokholyan nv. Mol Cancer Ther. 2020 Dec;19(12):2422-2431. doi: 10.1158/1535-7163.MCT-19-0949. Epub 2020 Oct 21. Mol Cancer Ther. 2020. PMID: 33087513 Free PMC article.
SOD1 oligomers in amyotrophic lateral sclerosis.
Choi ES, Dokholyan NV. Choi ES, et al. Among authors: dokholyan nv. Curr Opin Struct Biol. 2021 Feb;66:225-230. doi: 10.1016/j.sbi.2020.12.002. Epub 2021 Jan 16. Curr Opin Struct Biol. 2021. PMID: 33465527 Free PMC article. Review.
Activating Sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis.
Chen YC, Dinavahi SS, Feng Q, Gowda R, Ramisetti S, Xia X, LaPenna KB, Chirasani VR, Cho SH, Hafenstein SL, Battu MB, Berg A, Sharma AK, Kirchhausen T, Dokholyan NV, Amin S, He P, Robertson GP. Chen YC, et al. Among authors: dokholyan nv. Cancer Lett. 2021 May 28;506:107-119. doi: 10.1016/j.canlet.2021.01.004. Epub 2021 Feb 16. Cancer Lett. 2021. PMID: 33600895 Free PMC article.
Big versus small: The impact of aggregate size in disease.
Hnath B, Chen J, Reynolds J, Choi E, Wang J, Zhang D, Sha CM, Dokholyan NV. Hnath B, et al. Among authors: dokholyan nv. Protein Sci. 2023 Jul;32(7):e4686. doi: 10.1002/pro.4686. Protein Sci. 2023. PMID: 37243896 Free PMC article. Review.
328 results