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The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation.
Dhillon P, Park J, Hurtado Del Pozo C, Li L, Doke T, Huang S, Zhao J, Kang HM, Shrestra R, Balzer MS, Chatterjee S, Prado P, Han SY, Liu H, Sheng X, Dierickx P, Batmanov K, Romero JP, Prósper F, Li M, Pei L, Kim J, Montserrat N, Susztak K. Dhillon P, et al. Among authors: doke t. Cell Metab. 2021 Feb 2;33(2):379-394.e8. doi: 10.1016/j.cmet.2020.11.011. Epub 2020 Dec 9. Cell Metab. 2021. PMID: 33301705 Free PMC article.
DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity.
Cao A, Li J, Asadi M, Basgen JM, Zhu B, Yi Z, Jiang S, Doke T, El Shamy O, Patel N, Cravedi P, Azeloglu EU, Campbell KN, Menon M, Coca S, Zhang W, Wang H, Zen K, Liu Z, Murphy B, He JC, D'Agati VD, Susztak K, Kaufman L. Cao A, et al. Among authors: doke t. J Clin Invest. 2021 May 17;131(10):e141279. doi: 10.1172/JCI141279. J Clin Invest. 2021. PMID: 33998601 Free PMC article.
NAD+ flux is maintained in aged mice despite lower tissue concentrations.
McReynolds MR, Chellappa K, Chiles E, Jankowski C, Shen Y, Chen L, Descamps HC, Mukherjee S, Bhat YR, Lingala SR, Chu Q, Botolin P, Hayat F, Doke T, Susztak K, Thaiss CA, Lu W, Migaud ME, Su X, Rabinowitz JD, Baur JA. McReynolds MR, et al. Among authors: doke t. Cell Syst. 2021 Dec 15;12(12):1160-1172.e4. doi: 10.1016/j.cels.2021.09.001. Epub 2021 Sep 23. Cell Syst. 2021. PMID: 34559996 Free PMC article.
Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis.
Doke T, Abedini A, Aldridge DL, Yang YW, Park J, Hernandez CM, Balzer MS, Shrestra R, Coppock G, Rico JMI, Han SY, Kim J, Xin S, Piliponsky AM, Angelozzi M, Lefebvre V, Siracusa MC, Hunter CA, Susztak K. Doke T, et al. Nat Immunol. 2022 Jun;23(6):947-959. doi: 10.1038/s41590-022-01200-7. Epub 2022 May 12. Nat Immunol. 2022. PMID: 35552540
Molecular pathways that drive diabetic kidney disease.
Mohandes S, Doke T, Hu H, Mukhi D, Dhillon P, Susztak K. Mohandes S, et al. Among authors: doke t. J Clin Invest. 2023 Feb 15;133(4):e165654. doi: 10.1172/JCI165654. J Clin Invest. 2023. PMID: 36787250 Free PMC article. Review.
70 results