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Page 1
Targeting transglutaminase 2 mediated exostosin glycosyltransferase 1 signaling in liver cancer stem cells with acyclic retinoid.
Qin XY, Furutani Y, Yonezawa K, Shimizu N, Kato-Murayama M, Shirouzu M, Xu Y, Yamano Y, Wada A, Gailhouste L, Shrestha R, Takahashi M, Keillor JW, Su T, Yu W, Fujii S, Kagechika H, Dohmae N, Shirakami Y, Shimizu M, Masaki T, Matsuura T, Suzuki H, Kojima S. Qin XY, et al. Among authors: dohmae n. Cell Death Dis. 2023 Jun 13;14(6):358. doi: 10.1038/s41419-023-05847-4. Cell Death Dis. 2023. PMID: 37308486 Free PMC article.
Design, synthesis, and target identification of new hypoxia-inducible factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety.
Sakai M, Takahashi N, Ikeda H, Furutani Y, Higuchi S, Suzuki T, Dohmae N, Kobayashi S, Harada H, Kojima S, Matsuura T, Hattori A, Kakeya H. Sakai M, et al. Among authors: dohmae n. Bioorg Med Chem. 2021 Sep 15;46:116375. doi: 10.1016/j.bmc.2021.116375. Epub 2021 Aug 30. Bioorg Med Chem. 2021. PMID: 34492592
Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Kikuchi M, Morita S, Wakamori M, Sato S, Uchikubo-Kamo T, Suzuki T, Dohmae N, Shirouzu M, Umehara T. Kikuchi M, et al. Among authors: dohmae n. Nat Commun. 2023 Jul 17;14(1):4103. doi: 10.1038/s41467-023-39735-4. Nat Commun. 2023. PMID: 37460559 Free PMC article.
The two-step cargo recognition mechanism of heterotrimeric kinesin.
Jiang X, Ogawa T, Yonezawa K, Shimizu N, Ichinose S, Uchihashi T, Nagaike W, Moriya T, Adachi N, Kawasaki M, Dohmae N, Senda T, Hirokawa N. Jiang X, et al. Among authors: dohmae n. EMBO Rep. 2023 Nov 6;24(11):e56864. doi: 10.15252/embr.202356864. Epub 2023 Aug 14. EMBO Rep. 2023. PMID: 37575008 Free article.
A small molecule iCDM-34 identified by in silico screening suppresses HBV DNA through activation of aryl hydrocarbon receptor.
Furutani Y, Hirano Y, Toguchi M, Higuchi S, Qin XY, Yanaka K, Sato-Shiozaki Y, Takahashi N, Sakai M, Kongpracha P, Suzuki T, Dohmae N, Kukimoto-Niino M, Shirouzu M, Nagamori S, Suzuki H, Kobayashi K, Masaki T, Koyama H, Sekiba K, Otsuka M, Koike K, Kohara M, Kojima S, Kakeya H, Matsuura T. Furutani Y, et al. Among authors: dohmae n. Cell Death Discov. 2023 Dec 22;9(1):467. doi: 10.1038/s41420-023-01755-w. Cell Death Discov. 2023. PMID: 38135680 Free PMC article.
359 results