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Arylsulfonamide pyrimidines as VLA-4 antagonists.
Bioorg Med Chem Lett. 2013 May 15;23(10):3070-4. doi: 10.1016/j.bmcl.2013.03.010. Epub 2013 Mar 15.
Bioorg Med Chem Lett. 2013.
PMID: 23562062
PEG conjugates of potent α4 integrin inhibitors, maintaining sustained levels and bioactivity in vivo, following subcutaneous administration.
Smith JL, Rossiter KI, Semko CM, Xu YZ, Quincy DA, Jagodzinski J, Dappen MS, Konradi AW, Vandevert C, Garrido C, Mao W, San Pablo FB, Wipke B, Dofiles L, Wadsworth A, Peterson E, Lorenzana C, Simmonds S, Messersmith EK, Bard F, Pleiss MA, Yednock TA.
Smith JL, et al. Among authors: dofiles l.
Bioorg Med Chem Lett. 2013 Jul 15;23(14):4117-9. doi: 10.1016/j.bmcl.2013.05.048. Epub 2013 May 24.
Bioorg Med Chem Lett. 2013.
PMID: 23743283
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Orally available and efficacious α4β1/α4β7 integrin inhibitors.
Xu YZ, Smith JL, Semko CM, Rossiter KI, Fukuda JY, Dappen MS, Quincy DA, Konradi AW, Mao W, Welch B, Dreyer ML, Samant B, Zhang H, Lugar J, Liao Z, Henschel C, Petersen E, Vandevert C, Shoemaker M, Wehner N, Mutter L, Shopp G, Krimm M, Chen L, Wipke B, Dofiles L, Gallager I, Sauer JM, Messersmith EK, Pleiss MA, Bard F, Yednock TA.
Xu YZ, et al. Among authors: dofiles l.
Bioorg Med Chem Lett. 2013 Aug 1;23(15):4370-3. doi: 10.1016/j.bmcl.2013.05.076. Epub 2013 May 31.
Bioorg Med Chem Lett. 2013.
PMID: 23777782
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Effects of an alpha-4 integrin inhibitor on restenosis in a new porcine model combining endothelial denudation and stent placement.
Braun A, Dofiles L, Rousselle S, Guerrero L, Gunther J, Yednock T, Stricker-Krongrad A, Messersmith E.
Braun A, et al. Among authors: dofiles l.
PLoS One. 2010 Dec 13;5(12):e14314. doi: 10.1371/journal.pone.0014314.
PLoS One. 2010.
PMID: 21179441
Free PMC article.
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Development of an enzyme-linked immunosorbent assay (ELISA) to measure the level of tyrosine hydroxylase protein in brain tissue from Parkinson's disease models.
Fauss D, Motter R, Dofiles L, Rodrigues MA, You M, Diep L, Yang Y, Seto P, Tanaka K, Baker J, Bergeron M.
Fauss D, et al. Among authors: dofiles l.
J Neurosci Methods. 2013 May 15;215(2):245-57. doi: 10.1016/j.jneumeth.2013.03.012. Epub 2013 Mar 26.
J Neurosci Methods. 2013.
PMID: 23537934
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