Doepner M - Search Results

1

Targeting anti-apoptotic pathways eliminates senescent melanocytes and leads to nevi regression.

Kohli J, Ge C, Fitsiou E, Doepner M, Brandenburg SM, Faller WJ, Ridky TW, Demaria M. Kohli J, et al. Among authors: doepner m. Nat Commun. 2022 Dec 23;13(1):7923. doi: 10.1038/s41467-022-35657-9. Nat Commun. 2022. PMID: 36564381 Free PMC article.

2

LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors.

Egolf S, Aubert Y, Doepner M, Anderson A, Maldonado-Lopez A, Pacella G, Lee J, Ko EK, Zou J, Lan Y, Simpson CL, Ridky T, Capell BC. Egolf S, et al. Among authors: doepner m. Cell Rep. 2019 Aug 20;28(8):1981-1992.e7. doi: 10.1016/j.celrep.2019.07.058. Cell Rep. 2019. PMID: 31433976 Free PMC article.

3

Drug Resistant Melanoma May Be Vulnerable to Inhibitors of Serine Synthesis.

Doepner M, Lee IY, Ridky TW. Doepner M, et al. J Invest Dermatol. 2020 Nov;140(11):2114-2116. doi: 10.1016/j.jid.2020.05.103. J Invest Dermatol. 2020. PMID: 33099398 Free article.

4

Endogenous DOPA inhibits melanoma through suppression of CHRM1 signaling.

Doepner M, Lee I, Natale CA, Brathwaite R, Venkat S, Kim SH, Wei Y, Vakoc CR, Capell BC, Katzenellenbogen JA, Katzenellenbogen BS, Feigin ME, Ridky TW. Doepner M, et al. Sci Adv. 2022 Sep 2;8(35):eabn4007. doi: 10.1126/sciadv.abn4007. Epub 2022 Sep 2. Sci Adv. 2022. PMID: 36054350 Free PMC article.

5

LNS8801 inhibits Acute Myeloid Leukemia by Inducing the Production of Reactive Oxygen Species and Activating the Endoplasmic Reticulum Stress Pathway.

Lee I, Doepner M, Weissenrieder J, Majer AD, Mercado S, Estell A, Natale CA, Sung PJ, Foskett JK, Carroll MP, Ridky TW. Lee I, et al. Among authors: doepner m. Cancer Res Commun. 2023 Aug 18;3(8):1594-1606. doi: 10.1158/2767-9764.CRC-22-0478. eCollection 2023 Aug. Cancer Res Commun. 2023. PMID: 37599786 Free PMC article.

6

The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination.

Donaghy R, Han X, Rozenova K, Lv K, Jiang Q, Doepner M, Greenberg RA, Tong W. Donaghy R, et al. Among authors: doepner m. Blood. 2019 Apr 4;133(14):1560-1571. doi: 10.1182/blood-2018-10-877563. Epub 2019 Feb 12. Blood. 2019. PMID: 30755420 Free PMC article.

7

Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.

Sela Y, Li J, Maheswaran S, Norgard R, Yuan S, Hubbi M, Doepner M, Xu JP, Ho ES, Mesaros C, Sheehan C, Croley G, Muir A, Blair IA, Shalem O, Dang CV, Stanger BZ. Sela Y, et al. Among authors: doepner m. Cancer Res. 2022 May 16;82(10):1890-1908. doi: 10.1158/0008-5472.CAN-22-0431. Cancer Res. 2022. PMID: 35315913 Free PMC article.

8

Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway.

Wu Y, Doepner M, Hojnacki T, Feng Z, Katona BW, He X, Ma J, Cao Y, Busino L, Zhou F, Hua X. Wu Y, et al. Among authors: doepner m. Am J Cancer Res. 2019 Aug 1;9(8):1682-1694. eCollection 2019. Am J Cancer Res. 2019. PMID: 31497350 Free PMC article.

9

Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma.

Lopez G, Conkrite KL, Doepner M, Rathi KS, Modi A, Vaksman Z, Farra LM, Hyson E, Noureddine M, Wei JS, Smith MA, Asgharzadeh S, Seeger RC, Khan J, Auvil JG, Gerhard DS, Maris JM, Diskin SJ. Lopez G, et al. Among authors: doepner m. Genome Res. 2020 Sep;30(9):1228-1242. doi: 10.1101/gr.252106.119. Epub 2020 Aug 13. Genome Res. 2020. PMID: 32796005 Free PMC article.

10

Pharmacokinetics of tazobactam M1 metabolite after administration of piperacillin/tazobactam in subjects with renal impairment.

Halstenson CE, Wong MO, Johnson CA, Zimmerman SW, Onorato JJ, Keane WF, Doepner M, Sia L, Tantillo K, Bansal S, et al. Halstenson CE, et al. Among authors: doepner m. J Clin Pharmacol. 1994 Dec;34(12):1208-17. doi: 10.1002/j.1552-4604.1994.tb04733.x. J Clin Pharmacol. 1994. PMID: 7738217

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