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A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord.
Cavone L, McCann T, Drake LK, Aguzzi EA, Oprişoreanu AM, Pedersen E, Sandi S, Selvarajah J, Tsarouchas TM, Wehner D, Keatinge M, Mysiak KS, Henderson BEP, Dobie R, Henderson NC, Becker T, Becker CG. Cavone L, et al. Among authors: dobie r. Dev Cell. 2021 Jun 7;56(11):1617-1630.e6. doi: 10.1016/j.devcel.2021.04.031. Epub 2021 May 24. Dev Cell. 2021. PMID: 34033756 Free article.
A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.
Minutti CM, Modak RV, Macdonald F, Li F, Smyth DJ, Dorward DA, Blair N, Husovsky C, Muir A, Giampazolias E, Dobie R, Maizels RM, Kendall TJ, Griggs DW, Kopf M, Henderson NC, Zaiss DM. Minutti CM, et al. Among authors: dobie r. Immunity. 2019 Mar 19;50(3):645-654.e6. doi: 10.1016/j.immuni.2019.01.008. Epub 2019 Feb 12. Immunity. 2019. PMID: 30770250 Free PMC article.
Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction.
Li Z, Solomonidis EG, Meloni M, Taylor RS, Duffin R, Dobie R, Magalhaes MS, Henderson BEP, Louwe PA, D'Amico G, Hodivala-Dilke KM, Shah AM, Mills NL, Simons BD, Gray GA, Henderson NC, Baker AH, Brittan M. Li Z, et al. Among authors: dobie r. Eur Heart J. 2019 Aug 7;40(30):2507-2520. doi: 10.1093/eurheartj/ehz305. Eur Heart J. 2019. PMID: 31162546 Free PMC article.
Resolving the fibrotic niche of human liver cirrhosis at single-cell level.
Ramachandran P, Dobie R, Wilson-Kanamori JR, Dora EF, Henderson BEP, Luu NT, Portman JR, Matchett KP, Brice M, Marwick JA, Taylor RS, Efremova M, Vento-Tormo R, Carragher NO, Kendall TJ, Fallowfield JA, Harrison EM, Mole DJ, Wigmore SJ, Newsome PN, Weston CJ, Iredale JP, Tacke F, Pollard JW, Ponting CP, Marioni JC, Teichmann SA, Henderson NC. Ramachandran P, et al. Among authors: dobie r. Nature. 2019 Nov;575(7783):512-518. doi: 10.1038/s41586-019-1631-3. Epub 2019 Oct 9. Nature. 2019. PMID: 31597160 Free PMC article.
Unravelling fibrosis using single-cell transcriptomics.
Dobie R, Henderson NC. Dobie R, et al. Curr Opin Pharmacol. 2019 Dec;49:71-75. doi: 10.1016/j.coph.2019.09.004. Epub 2019 Oct 25. Curr Opin Pharmacol. 2019. PMID: 31670054 Free article. Review.
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Dobie R, Wilson-Kanamori JR, Henderson BEP, Smith JR, Matchett KP, Portman JR, Wallenborg K, Picelli S, Zagorska A, Pendem SV, Hudson TE, Wu MM, Budas GR, Breckenridge DG, Harrison EM, Mole DJ, Wigmore SJ, Ramachandran P, Ponting CP, Teichmann SA, Marioni JC, Henderson NC. Dobie R, et al. Cell Rep. 2019 Nov 12;29(7):1832-1847.e8. doi: 10.1016/j.celrep.2019.10.024. Cell Rep. 2019. PMID: 31722201 Free PMC article.
Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants.
Jackson-Jones LH, Smith P, Portman JR, Magalhaes MS, Mylonas KJ, Vermeren MM, Nixon M, Henderson BEP, Dobie R, Vermeren S, Denby L, Henderson NC, Mole DJ, Bénézech C. Jackson-Jones LH, et al. Among authors: dobie r. Immunity. 2020 Apr 14;52(4):700-715.e6. doi: 10.1016/j.immuni.2020.03.011. Immunity. 2020. PMID: 32294409 Free PMC article.
185 results