Multistage and mixture parallel gatekeeping procedures in clinical trials.
Dmitrienko A, Kordzakhia G, Tamhane AC.
Dmitrienko A, et al.
J Biopharm Stat. 2011 Jul;21(4):726-47. doi: 10.1080/10543406.2011.551333.
J Biopharm Stat. 2011.
PMID: 21516566
Gatekeeping procedures have been developed to solve multiplicity problems arising in clinical trials with hierarchical objectives where the null hypotheses that address these objectives are grouped into ordered families. A general method for constructing multistage paralle …
Gatekeeping procedures have been developed to solve multiplicity problems arising in clinical trials with hierarchical objectives where the …