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Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice.
Verhaegen ME, Harms PW, Van Goor JJ, Arche J, Patrick MT, Wilbert D, Zabawa H, Grachtchouk M, Liu CJ, Hu K, Kelly MC, Chen P, Saunders TL, Weidinger S, Syu LJ, Runge JS, Gudjonsson JE, Wong SY, Brownell I, Cieslik M, Udager AM, Chinnaiyan AM, Tsoi LC, Dlugosz AA. Verhaegen ME, et al. Among authors: dlugosz aa. J Clin Invest. 2022 Apr 1;132(7):e152069. doi: 10.1172/JCI152069. J Clin Invest. 2022. PMID: 35143422 Free PMC article.
Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis.
Harms PW, Patel RM, Verhaegen ME, Giordano TJ, Nash KT, Johnson CN, Daignault S, Thomas DG, Gudjonsson JE, Elder JT, Dlugosz AA, Johnson TM, Fullen DR, Bichakjian CK. Harms PW, et al. Among authors: dlugosz aa. J Invest Dermatol. 2013 Apr;133(4):936-45. doi: 10.1038/jid.2012.445. Epub 2012 Dec 6. J Invest Dermatol. 2013. PMID: 23223137 Free PMC article.
Merkel cell carcinoma dependence on bcl-2 family members for survival.
Verhaegen ME, Mangelberger D, Weick JW, Vozheiko TD, Harms PW, Nash KT, Quintana E, Baciu P, Johnson TM, Bichakjian CK, Dlugosz AA. Verhaegen ME, et al. Among authors: dlugosz aa. J Invest Dermatol. 2014 Aug;134(8):2241-2250. doi: 10.1038/jid.2014.138. Epub 2014 Mar 10. J Invest Dermatol. 2014. PMID: 24614157 Free PMC article.
Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.
Verhaegen ME, Mangelberger D, Harms PW, Vozheiko TD, Weick JW, Wilbert DM, Saunders TL, Ermilov AN, Bichakjian CK, Johnson TM, Imperiale MJ, Dlugosz AA. Verhaegen ME, et al. Among authors: dlugosz aa. J Invest Dermatol. 2015 May;135(5):1415-1424. doi: 10.1038/jid.2014.446. Epub 2014 Oct 14. J Invest Dermatol. 2015. PMID: 25313532 Free PMC article.
Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation.
Harms PW, Collie AM, Hovelson DH, Cani AK, Verhaegen ME, Patel RM, Fullen DR, Omata K, Dlugosz AA, Tomlins SA, Billings SD. Harms PW, et al. Among authors: dlugosz aa. Mod Pathol. 2016 Mar;29(3):240-8. doi: 10.1038/modpathol.2015.154. Epub 2016 Jan 8. Mod Pathol. 2016. PMID: 26743471 Free PMC article.
140 results