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Mortal hyperkalemia disturbances in rats are NO-system related. The life saving effect of pentadecapeptide BPC 157.
Barisic I, Balenovic D, Klicek R, Radic B, Nikitovic B, Drmic D, Udovicic M, Strinic D, Bardak D, Berkopic L, Djuzel V, Sever M, Cvjetko I, Romic Z, Sindic A, Bencic ML, Seiwerth S, Sikiric P. Barisic I, et al. Among authors: djuzel v. Regul Pept. 2013 Feb 10;181:50-66. doi: 10.1016/j.regpep.2012.12.007. Epub 2013 Jan 14. Regul Pept. 2013. PMID: 23327997
Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions.
Ilic S, Drmic D, Franjic S, Kolenc D, Coric M, Brcic L, Klicek R, Radic B, Sever M, Djuzel V, Filipovic M, Djakovic Z, Stambolija V, Blagaic AB, Zoricic I, Gjurasin M, Stupnisek M, Romic Z, Zarkovic K, Dzidic S, Seiwerth S, Sikiric P. Ilic S, et al. Among authors: djuzel v. Life Sci. 2011 Mar 14;88(11-12):535-42. doi: 10.1016/j.lfs.2011.01.015. Epub 2011 Feb 2. Life Sci. 2011. PMID: 21295044
High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736).
Ilic S, Drmic D, Zarkovic K, Kolenc D, Coric M, Brcic L, Klicek R, Radic B, Sever M, Djuzel V, Ivica M, Boban Blagaic A, Zoricic Z, Anic T, Zoricic I, Djidic S, Romic Z, Seiwerth S, Sikiric P. Ilic S, et al. Among authors: djuzel v. J Physiol Pharmacol. 2010 Apr;61(2):241-50. J Physiol Pharmacol. 2010. PMID: 20436226 Free article.
BPC 157 antagonized the general anaesthetic potency of thiopental and reduced prolongation of anaesthesia induced by L-NAME/thiopental combination.
Zemba M, Cilic AZ, Balenovic I, Cilic M, Radic B, Suran J, Drmic D, Kokot A, Stambolija V, Murselovic T, Holjevac JK, Uzun S, Djuzel V, Vlainic J, Seiwerth S, Sikiric P. Zemba M, et al. Among authors: djuzel v. Inflammopharmacology. 2015 Dec;23(6):329-36. doi: 10.1007/s10787-015-0249-9. Epub 2015 Nov 13. Inflammopharmacology. 2015. PMID: 26563892