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The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target.
Rona G, Zeke A, Miwatani-Minter B, de Vries M, Kaur R, Schinlever A, Garcia SF, Goldberg HV, Wang H, Hinds TR, Bailly F, Zheng N, Cotelle P, Desmaële D, Landau NR, Dittmann M, Pagano M. Rona G, et al. Among authors: dittmann m. Cell Death Differ. 2022 Feb;29(2):285-292. doi: 10.1038/s41418-021-00900-1. Epub 2021 Dec 3. Cell Death Differ. 2022. PMID: 34862481 Free PMC article.
The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response.
Seifert LL, Si C, Saha D, Sadic M, de Vries M, Ballentine S, Briley A, Wang G, Valero-Jimenez AM, Mohamed A, Schaefer U, Moulton HM, García-Sastre A, Tripathi S, Rosenberg BR, Dittmann M. Seifert LL, et al. Among authors: dittmann m. PLoS Pathog. 2019 Nov 4;15(11):e1007634. doi: 10.1371/journal.ppat.1007634. eCollection 2019 Nov. PLoS Pathog. 2019. PMID: 31682641 Free PMC article.
Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoV.
Lokugamage KG, Hage A, de Vries M, Valero-Jimenez AM, Schindewolf C, Dittmann M, Rajsbaum R, Menachery VD. Lokugamage KG, et al. Among authors: dittmann m. J Virol. 2020 Nov 9;94(23):e01410-20. doi: 10.1128/JVI.01410-20. Print 2020 Nov 9. J Virol. 2020. PMID: 32938761 Free PMC article.
A comparative analysis of SARS-CoV-2 antivirals characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19.
de Vries M, Mohamed AS, Prescott RA, Valero-Jimenez AM, Desvignes L, O'Connor R, Steppan C, Devlin JC, Ivanova E, Herrera A, Schinlever A, Loose P, Ruggles K, Koralov SB, Anderson AS, Binder J, Dittmann M. de Vries M, et al. Among authors: dittmann m. J Virol. 2021 Mar 10;95(7):e01819-20. doi: 10.1128/JVI.01819-20. Epub 2021 Feb 23. J Virol. 2021. PMID: 33622961 Free PMC article.
Antibody isotype diversity against SARS-CoV-2 is associated with differential serum neutralization capacities.
Noval MG, Kaczmarek ME, Koide A, Rodriguez-Rodriguez BA, Louie P, Tada T, Hattori T, Panchenko T, Romero LA, Teng KW, Bazley A, de Vries M, Samanovic MI, Weiser JN, Aifantis I, Cangiarella J, Mulligan MJ, Desvignes L, Dittmann M, Landau NR, Aguero-Rosenfeld M, Koide S, Stapleford KA. Noval MG, et al. Among authors: dittmann m. Sci Rep. 2021 Mar 10;11(1):5538. doi: 10.1038/s41598-021-84913-3. Sci Rep. 2021. PMID: 33692390 Free PMC article.
ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection.
Ching KL, de Vries M, Gago J, Dancel-Manning K, Sall J, Rice WJ, Barnett C, Khodadadi-Jamayran A, Tsirigos A, Liang FX, Thorpe LE, Shopsin B, Segal LN, Dittmann M, Torres VJ, Cadwell K. Ching KL, et al. Among authors: dittmann m. PLoS Biol. 2022 Sep 13;20(9):e3001754. doi: 10.1371/journal.pbio.3001754. eCollection 2022 Sep. PLoS Biol. 2022. PMID: 36099266 Free PMC article.
A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8.
Rodriguez-Rodriguez BA, Ciabattoni GO, Duerr R, Valero-Jimenez AM, Yeung ST, Crosse KM, Schinlever AR, Bernard-Raichon L, Rodriguez Galvan J, McGrath ME, Vashee S, Xue Y, Loomis CA, Khanna KM, Cadwell K, Desvignes L, Frieman MB, Ortigoza MB, Dittmann M. Rodriguez-Rodriguez BA, et al. Among authors: dittmann m. Nat Commun. 2023 May 25;14(1):3026. doi: 10.1038/s41467-023-38783-0. Nat Commun. 2023. PMID: 37230979 Free PMC article.
A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution.
Prescott RA, Pankow AP, de Vries M, Crosse KM, Patel RS, Alu M, Loomis C, Torres V, Koralov S, Ivanova E, Dittmann M, Rosenberg BR. Prescott RA, et al. Among authors: dittmann m. Respir Res. 2023 Aug 28;24(1):213. doi: 10.1186/s12931-023-02514-2. Respir Res. 2023. PMID: 37635251 Free PMC article.
Generation of quality-controlled SARS-CoV-2 variant stocks.
de Vries M, Ciabattoni GO, Rodriguez-Rodriguez BA, Crosse KM, Papandrea D, Samanovic MI, Dimartino D, Marier C, Mulligan MJ, Heguy A, Desvignes L, Duerr R, Dittmann M. de Vries M, et al. Among authors: dittmann m. Nat Protoc. 2023 Dec;18(12):3821-3855. doi: 10.1038/s41596-023-00897-6. Epub 2023 Oct 13. Nat Protoc. 2023. PMID: 37833423 Review.
Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV.
Lokugamage KG, Hage A, de Vries M, Valero-Jimenez AM, Schindewolf C, Dittmann M, Rajsbaum R, Menachery VD. Lokugamage KG, et al. Among authors: dittmann m. bioRxiv [Preprint]. 2020 Jul 13:2020.03.07.982264. doi: 10.1101/2020.03.07.982264. bioRxiv. 2020. PMID: 32511335 Free PMC article. Updated. Preprint.
132 results