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Page 1
T cell development critically depends on prethymic stromal patched expression.
Uhmann A, van den Brandt J, Dittmann K, Hess I, Dressel R, Binder C, Lühder F, Christiansen H, Fassnacht M, Bhandoola A, Wienands J, Reichardt HM, Hahn H. Uhmann A, et al. Among authors: dittmann k. J Immunol. 2011 Mar 15;186(6):3383-91. doi: 10.4049/jimmunol.1001939. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317383
The Hedgehog receptor Patched controls lymphoid lineage commitment.
Uhmann A, Dittmann K, Nitzki F, Dressel R, Koleva M, Frommhold A, Zibat A, Binder C, Adham I, Nitsche M, Heller T, Armstrong V, Schulz-Schaeffer W, Wienands J, Hahn H. Uhmann A, et al. Among authors: dittmann k. Blood. 2007 Sep 15;110(6):1814-23. doi: 10.1182/blood-2007-02-075648. Epub 2007 May 29. Blood. 2007. PMID: 17536012 Free article.
DMBA/TPA treatment is necessary for BCC formation from patched deficient epidermal cells in Ptch(flox/flox)CD4Cre(+/-) mice.
Uhmann A, Heß I, Frommhold A, König S, Zabel S, Nitzki F, Dittmann K, Lühder F, Christiansen H, Reifenberger J, Schulz-Schaeffer W, Hahn H. Uhmann A, et al. Among authors: dittmann k. J Invest Dermatol. 2014 Oct;134(10):2620-2629. doi: 10.1038/jid.2014.157. Epub 2014 Mar 24. J Invest Dermatol. 2014. PMID: 24662765 Free article.
Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.
Pelczar P, Zibat A, van Dop WA, Heijmans J, Bleckmann A, Gruber W, Nitzki F, Uhmann A, Guijarro MV, Hernando E, Dittmann K, Wienands J, Dressel R, Wojnowski L, Binder C, Taguchi T, Beissbarth T, Hogendoorn PC, Antonescu CR, Rubin BP, Schulz-Schaeffer W, Aberger F, van den Brink GR, Hahn H. Pelczar P, et al. Among authors: dittmann k. Gastroenterology. 2013 Jan;144(1):134-144.e6. doi: 10.1053/j.gastro.2012.09.061. Epub 2012 Oct 3. Gastroenterology. 2013. PMID: 23041331 Free PMC article.
Empty liposomes induce antitumoral effects associated with macrophage responses distinct from those of the TLR1/2 agonist Pam3CSK 4 (BLP).
König S, Regen T, Dittmann K, Engelke M, Wienands J, Schwendener R, Hanisch UK, Pukrop T, Hahn H. König S, et al. Among authors: dittmann k. Cancer Immunol Immunother. 2013 Oct;62(10):1587-97. doi: 10.1007/s00262-013-1444-4. Epub 2013 Aug 6. Cancer Immunol Immunother. 2013. PMID: 23917775 Free PMC article. Clinical Trial.
125 results