Dite TA - Search Results

1

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress.

Ling NXY, Kaczmarek A, Hoque A, Davie E, Ngoei KRW, Morrison KR, Smiles WJ, Forte GM, Wang T, Lie S, Dite TA, Langendorf CG, Scott JW, Oakhill JS, Petersen J. Ling NXY, et al. Among authors: dite ta. Nat Metab. 2020 Jan;2(1):41-49. doi: 10.1038/s42255-019-0157-1. Epub 2020 Jan 20. Nat Metab. 2020. PMID: 31993556 Free PMC article.

2

Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.

Scott JW, Ling N, Issa SM, Dite TA, O'Brien MT, Chen ZP, Galic S, Langendorf CG, Steinberg GR, Kemp BE, Oakhill JS. Scott JW, et al. Among authors: dite ta. Chem Biol. 2014 May 22;21(5):619-27. doi: 10.1016/j.chembiol.2014.03.006. Epub 2014 Apr 17. Chem Biol. 2014. PMID: 24746562

3

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

Scott JW, Galic S, Graham KL, Foitzik R, Ling NX, Dite TA, Issa SM, Langendorf CG, Weng QP, Thomas HE, Kay TW, Birnberg NC, Steinberg GR, Kemp BE, Oakhill JS. Scott JW, et al. Among authors: dite ta. Chem Biol. 2015 Jun 18;22(6):705-11. doi: 10.1016/j.chembiol.2015.05.011. Chem Biol. 2015. PMID: 26091167

4

Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder.

Scott JW, Park E, Rodriguiz RM, Oakhill JS, Issa SM, O'Brien MT, Dite TA, Langendorf CG, Wetsel WC, Means AR, Kemp BE. Scott JW, et al. Among authors: dite ta. Sci Rep. 2015 Sep 23;5:14436. doi: 10.1038/srep14436. Sci Rep. 2015. PMID: 26395653 Free PMC article.

5

Impact of Genetic Variation on Human CaMKK2 Regulation by Ca²⁺-Calmodulin and Multisite Phosphorylation.

O'Brien MT, Oakhill JS, Ling NX, Langendorf CG, Hoque A, Dite TA, Means AR, Kemp BE, Scott JW. O'Brien MT, et al. Among authors: dite ta. Sci Rep. 2017 Feb 23;7:43264. doi: 10.1038/srep43264. Sci Rep. 2017. PMID: 28230171 Free PMC article.

6

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs.

Dite TA, Ling NXY, Scott JW, Hoque A, Galic S, Parker BL, Ngoei KRW, Langendorf CG, O'Brien MT, Kundu M, Viollet B, Steinberg GR, Sakamoto K, Kemp BE, Oakhill JS. Dite TA, et al. Nat Commun. 2017 Sep 18;8(1):571. doi: 10.1038/s41467-017-00628-y. Nat Commun. 2017. PMID: 28924239 Free PMC article.

7

Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.

Lindqvist LM, Frank D, McArthur K, Dite TA, Lazarou M, Oakhill JS, Kile BT, Vaux DL. Lindqvist LM, et al. Among authors: dite ta. Cell Death Differ. 2018 Mar;25(4):784-796. doi: 10.1038/s41418-017-0017-z. Epub 2017 Dec 11. Cell Death Differ. 2018. PMID: 29229994 Free PMC article.

8

Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells.

Oakhill JS, Scott JW, Dite TA. Oakhill JS, et al. Among authors: dite ta. Methods Mol Biol. 2018;1732:159-169. doi: 10.1007/978-1-4939-7598-3_10. Methods Mol Biol. 2018. PMID: 29480474

9

Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.

Ngoei KRW, Langendorf CG, Ling NXY, Hoque A, Varghese S, Camerino MA, Walker SR, Bozikis YE, Dite TA, Ovens AJ, Smiles WJ, Jacobs R, Huang H, Parker MW, Scott JW, Rider MH, Foitzik RC, Kemp BE, Baell JB, Oakhill JS. Ngoei KRW, et al. Among authors: dite ta. Cell Chem Biol. 2018 Jun 21;25(6):728-737.e9. doi: 10.1016/j.chembiol.2018.03.008. Epub 2018 Apr 12. Cell Chem Biol. 2018. PMID: 29657085 Free article.

10

AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.

Dite TA, Langendorf CG, Hoque A, Galic S, Rebello RJ, Ovens AJ, Lindqvist LM, Ngoei KRW, Ling NXY, Furic L, Kemp BE, Scott JW, Oakhill JS. Dite TA, et al. J Biol Chem. 2018 Jun 8;293(23):8874-8885. doi: 10.1074/jbc.RA118.003547. Epub 2018 Apr 25. J Biol Chem. 2018. PMID: 29695504 Free PMC article.

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