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Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity.
Dorn T, Goedel A, Lam JT, Haas J, Tian Q, Herrmann F, Bundschu K, Dobreva G, Schiemann M, Dirschinger R, Guo Y, Kühl SJ, Sinnecker D, Lipp P, Laugwitz KL, Kühl M, Moretti A. Dorn T, et al. Among authors: dirschinger r. Stem Cells. 2015 Apr;33(4):1113-29. doi: 10.1002/stem.1923. Stem Cells. 2015. PMID: 25524439 Free PMC article.
Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia.
Jung CB, Moretti A, Mederos y Schnitzler M, Iop L, Storch U, Bellin M, Dorn T, Ruppenthal S, Pfeiffer S, Goedel A, Dirschinger RJ, Seyfarth M, Lam JT, Sinnecker D, Gudermann T, Lipp P, Laugwitz KL. Jung CB, et al. EMBO Mol Med. 2012 Mar;4(3):180-91. doi: 10.1002/emmm.201100194. Epub 2012 Jan 25. EMBO Mol Med. 2012. PMID: 22174035 Free PMC article.
Induced pluripotent stem cells in cardiovascular research.
Sinnecker D, Dirschinger RJ, Goedel A, Moretti A, Lipp P, Laugwitz KL. Sinnecker D, et al. Rev Physiol Biochem Pharmacol. 2012;163:1-26. doi: 10.1007/112_2012_6. Rev Physiol Biochem Pharmacol. 2012. PMID: 22447279 Review.
Modeling long-QT syndromes with iPS cells.
Sinnecker D, Goedel A, Dorn T, Dirschinger RJ, Moretti A, Laugwitz KL. Sinnecker D, et al. J Cardiovasc Transl Res. 2013 Feb;6(1):31-6. doi: 10.1007/s12265-012-9416-1. Epub 2012 Oct 18. J Cardiovasc Transl Res. 2013. PMID: 23076501 Review.
Postextrasystolic blood pressure potentiation predicts poor outcome of cardiac patients.
Sinnecker D, Dirschinger RJ, Barthel P, Müller A, Morley-Davies A, Hapfelmeier A, Dommasch M, Huster KM, Hasenfuss G, Laugwitz KL, Malik M, Schmidt G. Sinnecker D, et al. J Am Heart Assoc. 2014 Jun 3;3(3):e000857. doi: 10.1161/JAHA.114.000857. J Am Heart Assoc. 2014. PMID: 24895163 Free PMC article. Clinical Trial.
36 results