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Page 1
Challenges in neoantigen-directed therapeutics.
Lybaert L, Lefever S, Fant B, Smits E, De Geest B, Breckpot K, Dirix L, Feldman SA, van Criekinge W, Thielemans K, van der Burg SH, Ott PA, Bogaert C. Lybaert L, et al. Among authors: dirix l. Cancer Cell. 2023 Jan 9;41(1):15-40. doi: 10.1016/j.ccell.2022.10.013. Epub 2022 Nov 10. Cancer Cell. 2023. PMID: 36368320 Free article. Review.
First-in-human phase Ib trial of M9241 (NHS-IL12) plus avelumab in patients with advanced solid tumors, including dose expansion in patients with advanced urothelial carcinoma.
Strauss J, Deville JL, Sznol M, Ravaud A, Maruzzo M, Pachynski RK, Gourdin TS, Maio M, Dirix L, Schlom J, Donahue RN, Tsai YT, Wang X, Vugmeyster Y, Beier F, Seebeck J, Schroeder A, Chennoufi S, Gulley JL. Strauss J, et al. Among authors: dirix l. J Immunother Cancer. 2023 May;11(5):e005813. doi: 10.1136/jitc-2022-005813. J Immunother Cancer. 2023. PMID: 37236636 Free PMC article. Clinical Trial.
Transcriptomic characterization of the histopathological growth patterns in breast cancer liver metastases.
Leduc S, Nguyen HL, Richard F, Zels G, Mahdami A, De Schepper M, Maetens M, Pabba A, Jaekers J, Latacz E, Bohlok A, Vanderheyden E, Van Brussel T, Boeckx B, Schepers R, Lambrechts D, Dirix L, Larsimont D, Vankerckhove S, Lucidi V, Topal B, Bachir I, Donckier V, Floris G, Vermeulen P, Desmedt C. Leduc S, et al. Among authors: dirix l. Clin Exp Metastasis. 2024 Mar 29. doi: 10.1007/s10585-024-10279-1. Online ahead of print. Clin Exp Metastasis. 2024. PMID: 38548918
XIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant.
Van Berckelaer C, Van Laere S, Lee S, Morse MA, Geradts J, Dirix L, Kockx M, Bertucci F, Van Dam P, Devi GR. Van Berckelaer C, et al. Among authors: dirix l. Transl Oncol. 2024 May;43:101907. doi: 10.1016/j.tranon.2024.101907. Epub 2024 Feb 27. Transl Oncol. 2024. PMID: 38412664 Free PMC article.
Validation of the Prognostic Performance of Breast Cancer Index in Hormone Receptor-Positive Postmenopausal Breast Cancer Patients in the TEAM Trial.
Bartlett JMS, Xu K, Wong J, Pond G, Zhang Y, Spears M, Salunga R, Mallon E, Taylor KJ, Hasenburg A, Markopoulos C, Dirix L, van de Velde CJH, Rea D, Schnabel CA, Treuner K, Bayani J. Bartlett JMS, et al. Among authors: dirix l. Clin Cancer Res. 2024 Apr 15;30(8):1509-1517. doi: 10.1158/1078-0432.CCR-23-2436. Clin Cancer Res. 2024. PMID: 38345755 Free PMC article.
Treatment Response, Tumor Infiltrating Lymphocytes and Clinical Outcomes in Inflammatory Breast Cancer-Treated with Neoadjuvant Systemic Therapy.
De Schepper M, Nguyen HL, Richard F, Rosias L, Lerebours F, Vion R, Clatot F, Berghian A, Maetens M, Leduc S, Isnaldi E, Molinelli C, Lambertini M, Grillo F, Zoppoli G, Dirix L, Punie K, Wildiers H, Smeets A, Nevelsteen I, Neven P, Vincent-Salomon A, Larsimont D, Duhem C, Viens P, Bertucci F, Biganzoli E, Vermeulen P, Floris G, Desmedt C. De Schepper M, et al. Among authors: dirix l. Cancer Res Commun. 2024 Jan 24;4(1):186-199. doi: 10.1158/2767-9764.CRC-23-0285. Cancer Res Commun. 2024. PMID: 38147006 Free PMC article.
Histopathological growth patterns and tumor-infiltrating lymphocytes in breast cancer liver metastases.
Leduc S, De Schepper M, Richard F, Maetens M, Pabba A, Borremans K, Jaekers J, Latacz E, Zels G, Bohlok A, Van Baelen K, Nguyen HL, Geukens T, Dirix L, Larsimont D, Vankerckhove S, Santos E, Oliveira RC, Dede K, Kulka J, Borbala S, Salamon F, Madaras L, Marcell Szasz A, Lucidi V, Meyer Y, Topal B, Verhoef C, Engstrand J, Moro CF, Gerling M, Bachir I, Biganzoli E, Donckier V, Floris G, Vermeulen P, Desmedt C. Leduc S, et al. Among authors: dirix l. NPJ Breast Cancer. 2023 Dec 15;9(1):100. doi: 10.1038/s41523-023-00602-6. NPJ Breast Cancer. 2023. PMID: 38102162 Free PMC article.
Histopathological growth pattern of liver metastases as an independent marker of metastatic behavior in different primary cancers.
Bohlok A, Richard F, Lucidi V, Asmar AE, Demetter P, Craciun L, Larsimont D, Hendlisz A, Van Laethem JL, Dirix L, Desmedt C, Vermeulen P, Donckier V. Bohlok A, et al. Among authors: dirix l. Front Oncol. 2023 Oct 27;13:1260880. doi: 10.3389/fonc.2023.1260880. eCollection 2023. Front Oncol. 2023. PMID: 37965465 Free PMC article.
Paclitaxel plus Eftilagimod Alpha, a Soluble LAG-3 Protein, in Metastatic, HR+ Breast Cancer: Results from AIPAC, a Randomized, Placebo Controlled Phase IIb Trial.
Wildiers H, Armstrong A, Cuypere E, Dalenc F, Dirix L, Chan S, Marme F, Schröder CP, Huober J, Duhoux FP, Vuylsteke P, Jager A, Brain E, Kuemmel S, Pápai Z, Menke-van der Houven van Oordt CW, Perjesi L, Mueller C, Brignone C, Triebel F. Wildiers H, et al. Among authors: dirix l. Clin Cancer Res. 2024 Feb 1;30(3):532-541. doi: 10.1158/1078-0432.CCR-23-1173. Clin Cancer Res. 2024. PMID: 37939105 Free PMC article. Clinical Trial.
443 results