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CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.
Kojima Y, Volkmer JP, McKenna K, Civelek M, Lusis AJ, Miller CL, Direnzo D, Nanda V, Ye J, Connolly AJ, Schadt EE, Quertermous T, Betancur P, Maegdefessel L, Matic LP, Hedin U, Weissman IL, Leeper NJ. Kojima Y, et al. Among authors: direnzo d. Nature. 2016 Aug 4;536(7614):86-90. doi: 10.1038/nature18935. Epub 2016 Jul 20. Nature. 2016. PMID: 27437576 Free PMC article.
CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels.
Nanda V, Downing KP, Ye J, Xiao S, Kojima Y, Spin JM, DiRenzo D, Nead KT, Connolly AJ, Dandona S, Perisic L, Hedin U, Maegdefessel L, Dalman J, Guo L, Zhao X, Kolodgie FD, Virmani R, Davis HR Jr, Leeper NJ. Nanda V, et al. Among authors: direnzo d. Circ Res. 2016 Jan 22;118(2):230-40. doi: 10.1161/CIRCRESAHA.115.307906. Epub 2015 Nov 23. Circ Res. 2016. PMID: 26596284 Free PMC article.
Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade.
Wang Y, Nanda V, Direnzo D, Ye J, Xiao S, Kojima Y, Howe KL, Jarr KU, Flores AM, Tsantilas P, Tsao N, Rao A, Newman AAC, Eberhard AV, Priest JR, Ruusalepp A, Pasterkamp G, Maegdefessel L, Miller CL, Lind L, Koplev S, Björkegren JLM, Owens GK, Ingelsson E, Weissman IL, Leeper NJ. Wang Y, et al. Among authors: direnzo d. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15818-15826. doi: 10.1073/pnas.2006348117. Epub 2020 Jun 15. Proc Natl Acad Sci U S A. 2020. PMID: 32541024 Free PMC article.
Genetics and Genomics of Coronary Artery Disease.
Pjanic M, Miller CL, Wirka R, Kim JB, DiRenzo DM, Quertermous T. Pjanic M, et al. Curr Cardiol Rep. 2016 Oct;18(10):102. doi: 10.1007/s11886-016-0777-y. Curr Cardiol Rep. 2016. PMID: 27586139 Free PMC article. Review.
39 results