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Sex and cell-specific gene expression in corticolimbic brain regions associated with psychiatric disorders revealed by bulk and single-nuclei RNA sequencing.
Fitzgerald E, Arcego DM, Shen MJ, O'Toole N, Wen X, Nagy C, Mostafavi S, Craig K, Silveira PP, Rayan NA, Diorio J, Meaney MJ, Zhang TY. Fitzgerald E, et al. Among authors: diorio j. EBioMedicine. 2023 Sep;95:104749. doi: 10.1016/j.ebiom.2023.104749. Epub 2023 Aug 5. EBioMedicine. 2023. PMID: 37549631 Free PMC article.
A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regions.
Hari Dass SA, McCracken K, Pokhvisneva I, Chen LM, Garg E, Nguyen TTT, Wang Z, Barth B, Yaqubi M, McEwen LM, MacIsaac JL, Diorio J, Kobor MS, O'Donnell KJ, Meaney MJ, Silveira PP. Hari Dass SA, et al. Among authors: diorio j. EBioMedicine. 2019 Apr;42:188-202. doi: 10.1016/j.ebiom.2019.03.051. Epub 2019 Mar 26. EBioMedicine. 2019. PMID: 30922963 Free PMC article.
Integrative multi-omics landscape of fluoxetine action across 27 brain regions reveals global increase in energy metabolism and region-specific chromatin remodelling.
Rayan NA, Kumar V, Aow J, Rastegar N, Lim MGL, O'Toole N, Aliwarga E, Arcego DM, Yeo HTG, Wong JY, Lee MY, Schmidt F, Haja HS, Tam WL, Zhang TY, Diorio J, Anacker C, Hen R, Parent C, Meaney MJ, Prabhakar S. Rayan NA, et al. Among authors: diorio j. Mol Psychiatry. 2022 Nov;27(11):4510-4525. doi: 10.1038/s41380-022-01725-1. Epub 2022 Sep 2. Mol Psychiatry. 2022. PMID: 36056172 Free PMC article.
A Glucocorticoid-Sensitive Hippocampal Gene Network Moderates the Impact of Early-Life Adversity on Mental Health Outcomes.
Arcego DM, Buschdorf JP, O'Toole N, Wang Z, Barth B, Pokhvisneva I, Rayan NA, Patel S, de Mendonça Filho EJ, Lee P, Tan J, Koh MX, Sim CM, Parent C, de Lima RMS, Clappison A, O'Donnell KJ, Dalmaz C, Arloth J, Provençal N, Binder EB, Diorio J, Silveira PP, Meaney MJ. Arcego DM, et al. Among authors: diorio j. Biol Psychiatry. 2024 Jan 1;95(1):48-61. doi: 10.1016/j.biopsych.2023.06.028. Epub 2023 Jul 3. Biol Psychiatry. 2024. PMID: 37406925 Free article.
93 results