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Multimodal molecular imaging system for pathway-specific reporter gene expression.
Rossi M, Massai L, Diamanti D, Fiengo P, De Rosa A, Magrini R, Magnoni L, Chellini S, Coniglio S, Diodato E, Pilli E, Caradonna NP, Sardone G, Monti M, Roggeri R, Lionetti V, Recchia F, Tunici P, Valensin S, Scali C, Pollio G, Porcari V. Rossi M, et al. Among authors: diodato e. Eur J Pharm Sci. 2016 Apr 30;86:136-42. doi: 10.1016/j.ejps.2016.03.006. Epub 2016 Mar 14. Eur J Pharm Sci. 2016. PMID: 26987608
Fused 3-Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity.
La Rosa S, Benicchi T, Bettinetti L, Ceccarelli I, Diodato E, Federico C, Fiengo P, Franceschini D, Gokce O, Heitz F, Lazzeroni G, Luthi-Carter R, Magnoni L, Miragliotta V, Scali C, Valacchi M. La Rosa S, et al. Among authors: diodato e. ACS Med Chem Lett. 2013 Aug 8;4(10):979-84. doi: 10.1021/ml400251g. eCollection 2013 Oct 10. ACS Med Chem Lett. 2013. PMID: 24900595 Free PMC article.
A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease.
Smith MR, Syed A, Lukacsovich T, Purcell J, Barbaro BA, Worthge SA, Wei SR, Pollio G, Magnoni L, Scali C, Massai L, Franceschini D, Camarri M, Gianfriddo M, Diodato E, Thomas R, Gokce O, Tabrizi SJ, Caricasole A, Landwehrmeyer B, Menalled L, Murphy C, Ramboz S, Luthi-Carter R, Westerberg G, Marsh JL. Smith MR, et al. Among authors: diodato e. Hum Mol Genet. 2014 Jun 1;23(11):2995-3007. doi: 10.1093/hmg/ddu010. Epub 2014 Jan 16. Hum Mol Genet. 2014. PMID: 24436303 Free PMC article.
An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease.
Süssmuth SD, Haider S, Landwehrmeyer GB, Farmer R, Frost C, Tripepi G, Andersen CA, Di Bacco M, Lamanna C, Diodato E, Massai L, Diamanti D, Mori E, Magnoni L, Dreyhaupt J, Schiefele K, Craufurd D, Saft C, Rudzinska M, Ryglewicz D, Orth M, Brzozy S, Baran A, Pollio G, Andre R, Tabrizi SJ, Darpo B, Westerberg G; PADDINGTON Consortium. Süssmuth SD, et al. Among authors: diodato e. Br J Clin Pharmacol. 2015 Mar;79(3):465-76. doi: 10.1111/bcp.12512. Br J Clin Pharmacol. 2015. PMID: 25223731 Free PMC article. Clinical Trial.