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Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.
Perets R, Wyant GA, Muto KW, Bijron JG, Poole BB, Chin KT, Chen JY, Ohman AW, Stepule CD, Kwak S, Karst AM, Hirsch MS, Setlur SR, Crum CP, Dinulescu DM, Drapkin R. Perets R, et al. Among authors: dinulescu dm. Cancer Cell. 2013 Dec 9;24(6):751-65. doi: 10.1016/j.ccr.2013.10.013. Cancer Cell. 2013. PMID: 24332043 Free PMC article.
Origin of clear cell carcinoma: nature or nurture?
Kolin DL, Dinulescu DM, Crum CP. Kolin DL, et al. Among authors: dinulescu dm. J Pathol. 2018 Feb;244(2):131-134. doi: 10.1002/path.5009. Epub 2018 Jan 2. J Pathol. 2018. PMID: 29178260
Inaugurating High-Throughput Profiling of Extracellular Vesicles for Earlier Ovarian Cancer Detection.
Jo A, Green A, Medina JE, Iyer S, Ohman AW, McCarthy ET, Reinhardt F, Gerton T, Demehin D, Mishra R, Kolin DL, Zheng H, Cheon J, Crum CP, Weinberg RA, Rueda BR, Castro CM, Dinulescu DM, Lee H. Jo A, et al. Among authors: dinulescu dm. Adv Sci (Weinh). 2023 Sep;10(27):e2301930. doi: 10.1002/advs.202301930. Epub 2023 Jul 23. Adv Sci (Weinh). 2023. PMID: 37485618 Free PMC article.
Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness.
Szotek PP, Pieretti-Vanmarcke R, Masiakos PT, Dinulescu DM, Connolly D, Foster R, Dombkowski D, Preffer F, Maclaughlin DT, Donahoe PK. Szotek PP, et al. Among authors: dinulescu dm. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11154-9. doi: 10.1073/pnas.0603672103. Epub 2006 Jul 18. Proc Natl Acad Sci U S A. 2006. PMID: 16849428 Free PMC article.
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy.
McAuliffe SM, Morgan SL, Wyant GA, Tran LT, Muto KW, Chen YS, Chin KT, Partridge JC, Poole BB, Cheng KH, Daggett J Jr, Cullen K, Kantoff E, Hasselbatt K, Berkowitz J, Muto MG, Berkowitz RS, Aster JC, Matulonis UA, Dinulescu DM. McAuliffe SM, et al. Among authors: dinulescu dm. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):E2939-48. doi: 10.1073/pnas.1206400109. Epub 2012 Sep 27. Proc Natl Acad Sci U S A. 2012. PMID: 23019585 Free PMC article.
Targeting platinum resistant disease in ovarian cancer.
Morgan SL, Medina JE, Taylor MM, Dinulescu DM. Morgan SL, et al. Among authors: dinulescu dm. Curr Med Chem. 2014;21(26):3009-20. doi: 10.2174/0929867321666140414102701. Curr Med Chem. 2014. PMID: 24735363
The promise and challenge of ovarian cancer models.
Hasan N, Ohman AW, Dinulescu DM. Hasan N, et al. Among authors: dinulescu dm. Transl Cancer Res. 2015 Feb;4(1):14-28. doi: 10.3978/j.issn.2218-676X.2015.01.02. Transl Cancer Res. 2015. PMID: 26114093 Free PMC article.
46 results