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Sustained translational repression by eIF2α-P mediates prion neurodegeneration.
Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Martin MG, Halliday M, Morgan J, Dinsdale D, Ortori CA, Barrett DA, Tsaytler P, Bertolotti A, Willis AE, Bushell M, Mallucci GR. Moreno JA, et al. Among authors: dinsdale d. Nature. 2012 May 6;485(7399):507-11. doi: 10.1038/nature11058. Nature. 2012. PMID: 22622579 Free PMC article.
Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease.
Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM. Tufi R, et al. Among authors: dinsdale d. Nat Cell Biol. 2014 Feb;16(2):157-66. doi: 10.1038/ncb2901. Epub 2014 Jan 19. Nat Cell Biol. 2014. PMID: 24441527 Free PMC article.
Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf).
Chernova T, Murphy FA, Galavotti S, Sun XM, Powley IR, Grosso S, Schinwald A, Zacarias-Cabeza J, Dudek KM, Dinsdale D, Le Quesne J, Bennett J, Nakas A, Greaves P, Poland CA, Donaldson K, Bushell M, Willis AE, MacFarlane M. Chernova T, et al. Among authors: dinsdale d. Curr Biol. 2017 Nov 6;27(21):3302-3314.e6. doi: 10.1016/j.cub.2017.09.007. Curr Biol. 2017. PMID: 29112861 Free PMC article.
Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.
Robinson SW, Bourgognon JM, Spiers JG, Breda C, Campesan S, Butcher A, Mallucci GR, Dinsdale D, Morone N, Mistry R, Smith TM, Guerra-Martin M, Challiss RAJ, Giorgini F, Steinert JR. Robinson SW, et al. Among authors: dinsdale d. PLoS Biol. 2018 Apr 9;16(4):e2003611. doi: 10.1371/journal.pbio.2003611. eCollection 2018 Apr. PLoS Biol. 2018. PMID: 29630591 Free PMC article.
Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease.
Chernova T, Sun XM, Powley IR, Galavotti S, Grosso S, Murphy FA, Miles GJ, Cresswell L, Antonov AV, Bennett J, Nakas A, Dinsdale D, Cain K, Bushell M, Willis AE, MacFarlane M. Chernova T, et al. Among authors: dinsdale d. Cell Death Differ. 2016 Jul;23(7):1152-64. doi: 10.1038/cdd.2015.165. Epub 2016 Feb 19. Cell Death Differ. 2016. PMID: 26891694 Free PMC article.
178 results