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Page 1
Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems.
Dijk F, Veenstra VL, Soer EC, Dings MPG, Zhao L, Halfwerk JB, Hooijer GK, Damhofer H, Marzano M, Steins A, Waasdorp C, Busch OR, Besselink MG, Tol JA, Welling L, van Rijssen LB, Klompmaker S, Wilmink HW, van Laarhoven HW, Medema JP, Vermeulen L, van Hooff SR, Koster J, Verheij J, van de Vijver MJ, Wang X, Bijlsma MF. Dijk F, et al. Among authors: dings mpg. Sci Rep. 2020 Jan 15;10(1):337. doi: 10.1038/s41598-019-56826-9. Sci Rep. 2020. PMID: 31941932 Free PMC article.
CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells.
Hartl L, Duitman J, Aberson HL, Chen K, Dijk F, Roelofs JJTH, Dings MPG, Hooijer GKJ, Hernanda PY, Pan Q, Busch OR, Besselink MGH, Boerman T, Peppelenbosch MP, Bijlsma MF, Spek CA. Hartl L, et al. Among authors: dings mpg. Cancers (Basel). 2020 Sep 7;12(9):2546. doi: 10.3390/cancers12092546. Cancers (Basel). 2020. PMID: 32906832 Free PMC article.
Neoadjuvant Chemoradiotherapy Combined with Atezolizumab for Resectable Esophageal Adenocarcinoma: A Single-arm Phase II Feasibility Trial (PERFECT).
van den Ende T, de Clercq NC, van Berge Henegouwen MI, Gisbertz SS, Geijsen ED, Verhoeven RHA, Meijer SL, Schokker S, Dings MPG, Bergman JJGHM, Haj Mohammad N, Ruurda JP, van Hillegersberg R, Mook S, Nieuwdorp M, de Gruijl TD, Soeratram TTD, Ylstra B, van Grieken NCT, Bijlsma MF, Hulshof MCCM, van Laarhoven HWM. van den Ende T, et al. Among authors: dings mpg. Clin Cancer Res. 2021 Jun 15;27(12):3351-3359. doi: 10.1158/1078-0432.CCR-20-4443. Epub 2021 Jan 27. Clin Cancer Res. 2021. PMID: 33504550 Clinical Trial.
Molecular characterization of colorectal cancer related peritoneal metastatic disease.
Lenos KJ, Bach S, Ferreira Moreno L, Ten Hoorn S, Sluiter NR, Bootsma S, Vieira Braga FA, Nijman LE, van den Bosch T, Miedema DM, van Dijk E, Ylstra B, Kulicke R, Davis FP, Stransky N, Smolen GA, Coebergh van den Braak RRJ, IJzermans JNM, Martens JWM, Hallam S, Beggs AD, Kops GJPL, Lansu N, Bastiaenen VP, Klaver CEL, Lecca MC, El Makrini K, Elbers CC, Dings MPG, van Noesel CJM, Kranenburg O, Medema JP, Koster J, Koens L, Punt CJA, Tanis PJ, de Hingh IH, Bijlsma MF, Tuynman JB, Vermeulen L. Lenos KJ, et al. Among authors: dings mpg. Nat Commun. 2022 Aug 4;13(1):4443. doi: 10.1038/s41467-022-32198-z. Nat Commun. 2022. PMID: 35927254 Free PMC article.
Serum levels of iCAF-derived osteoglycin predict favorable outcome in pancreatic cancer.
Dings MPG, Manoukian P, Waasdorp C, Quik JSE, Strijker M, Lodestijn SC, van Neerven SM, Moreno LF, de Oliveira RL, Bonsing BA, Bruno MJ, Busch OR, Doukas M, van Eijck CH, Mohammad NH, de Hingh IH, Molenaar QI, Besselink MG, Vermeulen L, Medema JP, van Laarhoven HWM, Bijlsma MF. Dings MPG, et al. Int J Cancer. 2023 Feb 1;152(3):511-523. doi: 10.1002/ijc.34276. Epub 2022 Sep 19. Int J Cancer. 2023. PMID: 36069222 Free PMC article.
Estrogen-related receptor alpha drives mitochondrial biogenesis and resistance to neoadjuvant chemoradiation in esophageal cancer.
Dings MPG, van der Zalm AP, Bootsma S, van Maanen TFJ, Waasdorp C, van den Ende T, Liu D, Bailey P, Koster J, Zwijnenburg DA, Spek CA, Klomp JPG, Oubrie A, Hooijer GKJ, Meijer SL, van Berge Henegouwen MI, Hulshof MC, Bergman J, Oyarce C, Medema JP, van Laarhoven HWM, Bijlsma MF. Dings MPG, et al. Cell Rep Med. 2022 Nov 15;3(11):100802. doi: 10.1016/j.xcrm.2022.100802. Epub 2022 Nov 4. Cell Rep Med. 2022. PMID: 36334593 Free PMC article.
Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases.
Bootsma S, Dings MPG, Kesselaar J, Helderman RFCPA, van Megesen K, Constantinides A, Moreno LF, Stelloo E, Scutigliani EM, Bokan B, Torang A, van Hooff SR, Zwijnenburg DA, Wouters VM, van de Vlasakker VCJ, Galanos LJK, Nijman LE, Logiantara A, Veenstra VL, Schlingemann S, van Piggelen S, van der Wel N, Krawczyk PM, Platteeuw JJ, Tuynman JB, de Hingh IH, Klomp JPG, Oubrie A, Snaebjornsson P, Medema JP, Oei AL, Kranenburg O, Elbers CC, Lenos KJ, Vermeulen L, Bijlsma MF. Bootsma S, et al. Among authors: dings mpg. Cell Rep Med. 2024 Apr 22:101523. doi: 10.1016/j.xcrm.2024.101523. Online ahead of print. Cell Rep Med. 2024. PMID: 38670098 Free article.
Impact of classical and basal-like molecular subtypes on overall survival in resected pancreatic cancer in the SPACIOUS-2 multicentre study.
Suurmeijer JA, Soer EC, Dings MPG, Kim Y, Strijker M, Bonsing BA, Brosens LAA, Busch OR, Groen JV, Halfwerk JBG, Slooff RAE, van Laarhoven HWM, Molenaar IQ, Offerhaus GJA, Morreau J, van de Vijver MJ, Fariña Sarasqueta A, Verheij J, Besselink MG, Bijlsma MF, Dijk F; Dutch Pancreatic Cancer Group. Suurmeijer JA, et al. Among authors: dings mpg. Br J Surg. 2022 Oct 14;109(11):1150-1155. doi: 10.1093/bjs/znac272. Br J Surg. 2022. PMID: 35979597 Free PMC article.