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Sequence-based drug design as a concept in computational drug design.
Chen L, Fan Z, Chang J, Yang R, Hou H, Guo H, Zhang Y, Yang T, Zhou C, Sui Q, Chen Z, Zheng C, Hao X, Zhang K, Cui R, Zhang Z, Ma H, Ding Y, Zhang N, Lu X, Luo X, Jiang H, Zhang S, Zheng M. Chen L, et al. Among authors: ding y. Nat Commun. 2023 Jul 14;14(1):4217. doi: 10.1038/s41467-023-39856-w. Nat Commun. 2023. PMID: 37452028 Free PMC article.
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.
Du D, Xu D, Zhu L, Stazi G, Zwergel C, Liu Y, Luo Z, Li Y, Zhang Y, Zhu K, Ding Y, Liu J, Fan S, Zhao K, Zhang N, Kong X, Jiang H, Chen K, Zhao K, Valente S, Min J, Duan W, Luo C. Du D, et al. Among authors: ding y. J Med Chem. 2021 Jun 24;64(12):8194-8207. doi: 10.1021/acs.jmedchem.0c02261. Epub 2021 Jun 2. J Med Chem. 2021. PMID: 34077206
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases.
Xiao S, Guo S, Han J, Sun Y, Wang M, Chen Y, Fang X, Yang F, Mu Y, Zhang L, Ding Y, Zhang N, Jiang H, Chen K, Zhao K, Luo C, Chen S. Xiao S, et al. Among authors: ding y. Nucleic Acids Res. 2022 Jan 25;50(2):e9. doi: 10.1093/nar/gkab989. Nucleic Acids Res. 2022. PMID: 34718755 Free PMC article.
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