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A de novo gain-of-function KCND3 mutation in early repolarization syndrome.
Takayama K, Ohno S, Ding WG, Ashihara T, Fukumoto D, Wada Y, Makiyama T, Kise H, Hoshiai M, Matsuura H, Horie M. Takayama K, et al. Among authors: ding wg. Heart Rhythm. 2019 Nov;16(11):1698-1706. doi: 10.1016/j.hrthm.2019.05.033. Epub 2019 Jun 4. Heart Rhythm. 2019. PMID: 31173922
Gain-of-function KCNH2 mutations in patients with Brugada syndrome.
Wang QI, Ohno S, Ding WG, Fukuyama M, Miyamoto A, Itoh H, Makiyama T, Wu J, Bai J, Hasegawa K, Shinohara T, Takahashi N, Shimizu A, Matsuura H, Horie M. Wang QI, et al. Among authors: ding wg. J Cardiovasc Electrophysiol. 2014 May;25(5):522-530. doi: 10.1111/jce.12361. Epub 2014 Jan 30. J Cardiovasc Electrophysiol. 2014. PMID: 24400717
Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation.
Sakaguchi T, Itoh H, Ding WG, Tsuji K, Nagaoka I, Oka Y, Ashihara T, Ito M, Yumoto Y, Zenda N, Higashi Y, Takeyama Y, Matsuura H, Horie M. Sakaguchi T, et al. Among authors: ding wg. J Pharmacol Sci. 2008 Dec;108(4):462-71. doi: 10.1254/jphs.08178fp. Epub 2008 Dec 5. J Pharmacol Sci. 2008. PMID: 19057127 Free article.
D85N, a KCNE1 polymorphism, is a disease-causing gene variant in long QT syndrome.
Nishio Y, Makiyama T, Itoh H, Sakaguchi T, Ohno S, Gong YZ, Yamamoto S, Ozawa T, Ding WG, Toyoda F, Kawamura M, Akao M, Matsuura H, Kimura T, Kita T, Horie M. Nishio Y, et al. Among authors: ding wg. J Am Coll Cardiol. 2009 Aug 25;54(9):812-9. doi: 10.1016/j.jacc.2009.06.005. J Am Coll Cardiol. 2009. PMID: 19695459 Free article.
Latent genetic backgrounds and molecular pathogenesis in drug-induced long-QT syndrome.
Itoh H, Sakaguchi T, Ding WG, Watanabe E, Watanabe I, Nishio Y, Makiyama T, Ohno S, Akao M, Higashi Y, Zenda N, Kubota T, Mori C, Okajima K, Haruna T, Miyamoto A, Kawamura M, Ishida K, Nagaoka I, Oka Y, Nakazawa Y, Yao T, Jo H, Sugimoto Y, Ashihara T, Hayashi H, Ito M, Imoto K, Matsuura H, Horie M. Itoh H, et al. Among authors: ding wg. Circ Arrhythm Electrophysiol. 2009 Oct;2(5):511-23. doi: 10.1161/CIRCEP.109.862649. Epub 2009 Aug 2. Circ Arrhythm Electrophysiol. 2009. PMID: 19843919
116 results