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SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.
Lu Q, Liu J, Zhao S, Gomez Castro MF, Laurent-Rolle M, Dong J, Ran X, Damani-Yokota P, Tang H, Karakousi T, Son J, Kaczmarek ME, Zhang Z, Yeung ST, McCune BT, Chen RE, Tang F, Ren X, Chen X, Hsu JCC, Teplova M, Huang B, Deng H, Long Z, Mudianto T, Jin S, Lin P, Du J, Zang R, Su TT, Herrera A, Zhou M, Yan R, Cui J, Zhu J, Zhou Q, Wang T, Ma J, Koralov SB, Zhang Z, Aifantis I, Segal LN, Diamond MS, Khanna KM, Stapleford KA, Cresswell P, Liu Y, Ding S, Xie Q, Wang J. Lu Q, et al. Among authors: ding s. Immunity. 2021 Jun 8;54(6):1304-1319.e9. doi: 10.1016/j.immuni.2021.05.006. Epub 2021 May 9. Immunity. 2021. PMID: 34048708 Free PMC article.
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes.
Zang R, Gomez Castro MF, McCune BT, Zeng Q, Rothlauf PW, Sonnek NM, Liu Z, Brulois KF, Wang X, Greenberg HB, Diamond MS, Ciorba MA, Whelan SPJ, Ding S. Zang R, et al. Among authors: ding s. Sci Immunol. 2020 May 13;5(47):eabc3582. doi: 10.1126/sciimmunol.abc3582. Sci Immunol. 2020. PMID: 32404436 Free PMC article.
Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2.
Case JB, Rothlauf PW, Chen RE, Liu Z, Zhao H, Kim AS, Bloyet LM, Zeng Q, Tahan S, Droit L, Ilagan MXG, Tartell MA, Amarasinghe G, Henderson JP, Miersch S, Ustav M, Sidhu S, Virgin HW, Wang D, Ding S, Corti D, Theel ES, Fremont DH, Diamond MS, Whelan SPJ. Case JB, et al. Among authors: ding s. SSRN [Preprint]. 2020 May 27:3606354. doi: 10.2139/ssrn.3606354. SSRN. 2020. PMID: 32714117 Free PMC article. Updated. Preprint.
Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2.
Case JB, Rothlauf PW, Chen RE, Liu Z, Zhao H, Kim AS, Bloyet LM, Zeng Q, Tahan S, Droit L, Ilagan MXG, Tartell MA, Amarasinghe G, Henderson JP, Miersch S, Ustav M, Sidhu S, Virgin HW, Wang D, Ding S, Corti D, Theel ES, Fremont DH, Diamond MS, Whelan SPJ. Case JB, et al. Among authors: ding s. Cell Host Microbe. 2020 Sep 9;28(3):475-485.e5. doi: 10.1016/j.chom.2020.06.021. Epub 2020 Jul 3. Cell Host Microbe. 2020. PMID: 32735849 Free PMC article.
JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis.
Son J, Huang S, Zeng Q, Bricker TL, Case JB, Zhou J, Zang R, Liu Z, Chang X, Harastani HH, Chen L, Castro MFG, Zhao Y, Kohio HP, Hou G, Fan B, Niu B, Guo R, Rothlauf PW, Bailey AL, Wang X, Shi PY, Martinez ED, Whelan SPJ, Diamond MS, Boon ACM, Li B, Ding S. Son J, et al. Among authors: ding s. bioRxiv [Preprint]. 2021 Jun 4:2020.09.24.312165. doi: 10.1101/2020.09.24.312165. bioRxiv. 2021. PMID: 32995798 Free PMC article. Updated. Preprint.
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion.
Zang R, Case JB, Yutuc E, Ma X, Shen S, Gomez Castro MF, Liu Z, Zeng Q, Zhao H, Son J, Rothlauf PW, Kreutzberger AJB, Hou G, Zhang H, Bose S, Wang X, Vahey MD, Mani K, Griffiths WJ, Kirchhausen T, Fremont DH, Guo H, Diwan A, Wang Y, Diamond MS, Whelan SPJ, Ding S. Zang R, et al. Among authors: ding s. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):32105-32113. doi: 10.1073/pnas.2012197117. Epub 2020 Nov 25. Proc Natl Acad Sci U S A. 2020. PMID: 33239446 Free PMC article.
6,292 results