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Page 1
IgG2 disulfide isoform conversion kinetics.
Liu YD, Wang T, Chou R, Chen L, Kannan G, Stevenson R, Goetze AM, Jiang XG, Huang G, Dillon TM, Flynn GC. Liu YD, et al. Among authors: dillon tm. Mol Immunol. 2013 Jun;54(2):217-26. doi: 10.1016/j.molimm.2012.12.005. Epub 2013 Jan 2. Mol Immunol. 2013. PMID: 23291144
Isomerization of a single aspartyl residue of anti-epidermal growth factor receptor immunoglobulin gamma2 antibody highlights the role avidity plays in antibody activity.
Rehder DS, Chelius D, McAuley A, Dillon TM, Xiao G, Crouse-Zeineddini J, Vardanyan L, Perico N, Mukku V, Brems DN, Matsumura M, Bondarenko PV. Rehder DS, et al. Among authors: dillon tm. Biochemistry. 2008 Feb 26;47(8):2518-30. doi: 10.1021/bi7018223. Epub 2008 Jan 31. Biochemistry. 2008. PMID: 18232715
Human IgG2 antibodies display disulfide-mediated structural isoforms.
Wypych J, Li M, Guo A, Zhang Z, Martinez T, Allen MJ, Fodor S, Kelner DN, Flynn GC, Liu YD, Bondarenko PV, Ricci MS, Dillon TM, Balland A. Wypych J, et al. Among authors: dillon tm. J Biol Chem. 2008 Jun 6;283(23):16194-205. doi: 10.1074/jbc.M709987200. Epub 2008 Mar 13. J Biol Chem. 2008. PMID: 18339624 Free PMC article.
Human IgG2 antibody disulfide rearrangement in vivo.
Liu YD, Chen X, Enk JZ, Plant M, Dillon TM, Flynn GC. Liu YD, et al. Among authors: dillon tm. J Biol Chem. 2008 Oct 24;283(43):29266-72. doi: 10.1074/jbc.M804787200. Epub 2008 Aug 19. J Biol Chem. 2008. PMID: 18713741 Free PMC article.
Protected hinge in the immunoglobulin G2-A2 disulfide isoform.
Liu YD, Chou RY, Dillon TM, Poppe L, Spahr C, Shi SD, Flynn GC. Liu YD, et al. Among authors: dillon tm. Protein Sci. 2014 Dec;23(12):1753-64. doi: 10.1002/pro.2557. Epub 2014 Oct 23. Protein Sci. 2014. PMID: 25264323 Free PMC article.
Impact of antibody subclass and disulfide isoform differences on the biological activity of CD200R and βklotho agonist antibodies.
Grujic O, Stevens J, Chou RY, Weiszmann JV, Sekirov L, Thomson C, Badh A, Grauer S, Chan B, Graham K, Manchulenko K, Dillon TM, Li Y, Foltz IN. Grujic O, et al. Among authors: dillon tm. Biochem Biophys Res Commun. 2017 May 13;486(4):985-991. doi: 10.1016/j.bbrc.2017.03.145. Epub 2017 Mar 28. Biochem Biophys Res Commun. 2017. PMID: 28363871
39 results