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Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.
Dong X, Limjunyawong N, Sypek EI, Wang G, Ortines RV, Youn C, Alphonse MP, Dikeman D, Wang Y, Lay M, Kothari R, Vasavda C, Pundir P, Goff L, Miller LS, Lu W, Garza LA, Kim BS, Archer NK, Dong X. Dong X, et al. Among authors: dikeman d. Immunity. 2022 Sep 13;55(9):1645-1662.e7. doi: 10.1016/j.immuni.2022.06.021. Epub 2022 Jul 25. Immunity. 2022. PMID: 35882236 Free PMC article.
Efficacy of a Multimechanistic Monoclonal Antibody Combination against Staphylococcus aureus Surgical Site Infections in Mice.
Ortines RV, Wang Y, Liu H, Dikeman DA, Pinsker BL, Miller RJ, Kim SE, Ackerman NE, Rizkallah JF, Marcello LT, Cohen TS, Tkaczyk C, Sellman BR, Miller LS. Ortines RV, et al. Antimicrob Agents Chemother. 2019 Jul 25;63(8):e00346-19. doi: 10.1128/AAC.00346-19. Print 2019 Aug. Antimicrob Agents Chemother. 2019. PMID: 31138566 Free PMC article.
Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections.
Miller RJ, Crosby HA, Schilcher K, Wang Y, Ortines RV, Mazhar M, Dikeman DA, Pinsker BL, Brown ID, Joyce DP, Zhang J, Archer NK, Liu H, Alphonse MP, Czupryna J, Anderson WR, Bernthal NM, Fortuno-Miranda L, Bulte JWM, Francis KP, Horswill AR, Miller LS. Miller RJ, et al. Among authors: dikeman da. Sci Rep. 2019 Nov 13;9(1):16663. doi: 10.1038/s41598-019-52982-0. Sci Rep. 2019. PMID: 31723175 Free PMC article.
Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease.
Patrick GJ, Liu H, Alphonse MP, Dikeman DA, Youn C, Otterson JC, Wang Y, Ravipati A, Mazhar M, Denny G, Ortines RV, Zhang E, Miller RJ, Dillen CA, Liu Q, Nolan SJ, Nguyen K, Marcello L, Do DC, Wier EM, Zhang Y, Caviness G, Klimowicz AC, Mierz DV, Fine JS, Sun G, Goldbach-Mansky R, Marusina AI, Merleev AA, Maverakis E, Garza LA, Milner JD, Gao P, Ramanujam M, Raymond EL, Archer NK, Miller LS. Patrick GJ, et al. Among authors: dikeman da. J Clin Invest. 2021 Mar 1;131(5):e143334. doi: 10.1172/JCI143334. J Clin Invest. 2021. PMID: 33645549 Free PMC article.
Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections.
Alphonse MP, Rubens JH, Ortines RV, Orlando NA, Patel AM, Dikeman D, Wang Y, Vuong I, Joyce DP, Zhang J, Mumtaz M, Liu H, Liu Q, Youn C, Patrick GJ, Ravipati A, Miller RJ, Archer NK, Miller LS. Alphonse MP, et al. Among authors: dikeman d. Sci Transl Med. 2021 Jul 7;13(601):eabe9887. doi: 10.1126/scitranslmed.abe9887. Sci Transl Med. 2021. PMID: 34233954 Free PMC article.
IL-6R/Signal Transducer and Activator of Transcription 3 Signaling in Keratinocytes rather than in T Cells Induces Psoriasis-Like Dermatitis in Mice.
Ravipati A, Nolan S, Alphonse M, Dikeman D, Youn C, Wang Y, Orlando N, Patrick G, Lee S, Ortines RV, Liu H, Miller RJ, Dillen CA, Marchitto M, Cai SS, Miller LS, Archer NK. Ravipati A, et al. Among authors: dikeman d. J Invest Dermatol. 2022 Apr;142(4):1126-1135.e4. doi: 10.1016/j.jid.2021.09.012. Epub 2021 Oct 7. J Invest Dermatol. 2022. PMID: 34626614 Free PMC article.
36 results