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The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.
Goldswain H, Dong X, Penrice-Randal R, Alruwaili M, Shawli GT, Prince T, Williamson MK, Raghwani J, Randle N, Jones B, Donovan-Banfield I, Salguero FJ, Tree JA, Hall Y, Hartley C, Erdmann M, Bazire J, Jearanaiwitayakul T, Semple MG, Openshaw PJM, Baillie JK; ISARIC4C Investigators; Emmett SR, Digard P, Matthews DA, Turtle L, Darby AC, Davidson AD, Carroll MW, Hiscox JA. Goldswain H, et al. Among authors: digard p. Genome Biol. 2023 Mar 13;24(1):47. doi: 10.1186/s13059-023-02881-5. Genome Biol. 2023. PMID: 36915185 Free PMC article.
The molecular basis of differential host responses to avian influenza viruses in avian species with differing susceptibility.
Morris KM, Mishra A, Raut AA, Gaunt ER, Borowska D, Kuo RI, Wang B, Vijayakumar P, Chingtham S, Dutta R, Baillie K, Digard P, Vervelde L, Burt DW, Smith J. Morris KM, et al. Among authors: digard p. Front Cell Infect Microbiol. 2023 Feb 28;13:1067993. doi: 10.3389/fcimb.2023.1067993. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36926515 Free PMC article.
CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy.
Sharp CP, Thompson BH, Nash TJ, Diebold O, Pinto RM, Thorley L, Lin YT, Sives S, Wise H, Clohisey Hendry S, Grey F, Vervelde L, Simmonds P, Digard P, Gaunt ER. Sharp CP, et al. Among authors: digard p. PLoS Pathog. 2023 May 5;19(5):e1011357. doi: 10.1371/journal.ppat.1011357. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37146066 Free PMC article.
Corrigendum: The molecular basis of differential host responses to avian influenza viruses in avian species with differing susceptibility.
Morris KM, Mishra A, Raut AA, Gaunt ER, Borowska D, Kuo RI, Wang B, Vijayakumar P, Chingtham S, Dutta R, Baillie K, Digard P, Vervelde L, Burt DW, Smith J. Morris KM, et al. Among authors: digard p. Front Cell Infect Microbiol. 2023 Apr 4;13:1194878. doi: 10.3389/fcimb.2023.1194878. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37082716 Free PMC article.
BTN3A3 evasion promotes the zoonotic potential of influenza A viruses.
Pinto RM, Bakshi S, Lytras S, Zakaria MK, Swingler S, Worrell JC, Herder V, Hargrave KE, Varjak M, Cameron-Ruiz N, Collados Rodriguez M, Varela M, Wickenhagen A, Loney C, Pei Y, Hughes J, Valette E, Turnbull ML, Furnon W, Gu Q, Orr L, Taggart A, Diebold O, Davis C, Boutell C, Grey F, Hutchinson E, Digard P, Monne I, Wootton SK, MacLeod MKL, Wilson SJ, Palmarini M. Pinto RM, et al. Among authors: digard p. Nature. 2023 Jul;619(7969):338-347. doi: 10.1038/s41586-023-06261-8. Epub 2023 Jun 28. Nature. 2023. PMID: 37380775
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