Isoprenylation of the G protein gamma subunit is both necessary and sufficient for beta gamma dimer-mediated stimulation of phospholipase C.
Dietrich A, Brazil D, Jensen ON, Meister M, Schrader M, Moomaw JF, Mann M, Illenberger D, Gierschik P.
Dietrich A, et al.
Biochemistry. 1996 Dec 3;35(48):15174-82. doi: 10.1021/bi960305j.
Biochemistry. 1996.
PMID: 8952464
We have previously shown that isoprenylation and/or additional post-translational processing of the G protein gamma 1 subunit carboxyl terminus is required for beta 1 gamma 1 subunit stimulation of phospholipase C-beta 2 (PLC beta 2) [Dietrich, A., Meister, M., Braz …
We have previously shown that isoprenylation and/or additional post-translational processing of the G protein gamma 1 subunit carboxyl termi …