Dieter MZ - Search Results

1

Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.

Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, Boehnke K, Baquero C, Hui YH, Chapman SC, Yang Y, Zeng Y, Bogner SM, Foreman RT, Capen A, Donoho GP, Van Horn RD, Barnard DS, Dempsey JA, Beckmann RP, Marshall MS, Chio LC, Qian Y, Webster YW, Aggarwal A, Chu S, Bhattachar S, Stancato LF, Dowless MS, Iversen PW, Manro JR, Walgren JL, Halstead BW, Dieter MZ, Martinez R, Bhagwat SV, Kreklau EL, Lallena MJ, Ye XS, Patel BKR, Reinhard C, Plowman GD, Barda DA, Henry JR, Buchanan SG, Campbell RM. Du J, et al. Among authors: dieter mz. Mol Cancer Ther. 2019 Dec;18(12):2207-2219. doi: 10.1158/1535-7163.MCT-18-0529. Epub 2019 Sep 17. Mol Cancer Ther. 2019. PMID: 31530649

2

Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene.

Gong X, Du J, Parsons SH, Merzoug FF, Webster Y, Iversen PW, Chio LC, Van Horn RD, Lin X, Blosser W, Han B, Jin S, Yao S, Bian H, Ficklin C, Fan L, Kapoor A, Antonysamy S, Mc Nulty AM, Froning K, Manglicmot D, Pustilnik A, Weichert K, Wasserman SR, Dowless M, Marugán C, Baquero C, Lallena MJ, Eastman SW, Hui YH, Dieter MZ, Doman T, Chu S, Qian HR, Ye XS, Barda DA, Plowman GD, Reinhard C, Campbell RM, Henry JR, Buchanan SG. Gong X, et al. Among authors: dieter mz. Cancer Discov. 2019 Feb;9(2):248-263. doi: 10.1158/2159-8290.CD-18-0469. Epub 2018 Oct 29. Cancer Discov. 2019. PMID: 30373917

3

Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous.

Dalton TP, Dieter MZ, Yang Y, Shertzer HG, Nebert DW. Dalton TP, et al. Among authors: dieter mz. Biochem Biophys Res Commun. 2000 Dec 20;279(2):324-9. doi: 10.1006/bbrc.2000.3930. Biochem Biophys Res Commun. 2000. PMID: 11118286

4

Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis.

Nebert DW, Roe AL, Dieter MZ, Solis WA, Yang Y, Dalton TP. Nebert DW, et al. Among authors: dieter mz. Biochem Pharmacol. 2000 Jan 1;59(1):65-85. doi: 10.1016/s0006-2952(99)00310-x. Biochem Pharmacol. 2000. PMID: 10605936 Review.

5

Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress.

Solis WA, Dalton TP, Dieter MZ, Freshwater S, Harrer JM, He L, Shertzer HG, Nebert DW. Solis WA, et al. Among authors: dieter mz. Biochem Pharmacol. 2002 May 1;63(9):1739-54. doi: 10.1016/s0006-2952(02)00897-3. Biochem Pharmacol. 2002. PMID: 12007577

6

Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery.

Dalton TP, Dieter MZ, Matlib RS, Childs NL, Shertzer HG, Genter MB, Nebert DW. Dalton TP, et al. Among authors: dieter mz. Biochem Biophys Res Commun. 2000 Jan 7;267(1):184-9. doi: 10.1006/bbrc.1999.1913. Biochem Biophys Res Commun. 2000. PMID: 10623596

7

The evolution of drug metabolism.

Nebert DW, Dieter MZ. Nebert DW, et al. Among authors: dieter mz. Pharmacology. 2000 Sep;61(3):124-35. doi: 10.1159/000028393. Pharmacology. 2000. PMID: 10971198 Review.

8

Tyrphostin [correction of Tryphostin] AG879, a tyrosine kinase inhibitor: prevention of transcriptional activation of the electrophile and the aromatic hydrocarbon response elements.

Dieter MZ, Freshwater SL, Solis WA, Nebert DW, Dalton TP. Dieter MZ, et al. Biochem Pharmacol. 2001 Jan 15;61(2):215-25. doi: 10.1016/s0006-2952(00)00525-6. Biochem Pharmacol. 2001. PMID: 11163336

9

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response.

Yang Y, Dieter MZ, Chen Y, Shertzer HG, Nebert DW, Dalton TP. Yang Y, et al. Among authors: dieter mz. J Biol Chem. 2002 Dec 20;277(51):49446-52. doi: 10.1074/jbc.M209372200. Epub 2002 Oct 15. J Biol Chem. 2002. PMID: 12384496 Free article.

10

Pharmacological rescue of the 14CoS/14CoS mouse: hepatocyte apoptosis is likely caused by endogenous oxidative stress.

Dieter MZ, Freshwater SL, Miller ML, Shertzer HG, Dalton TP, Nebert DW. Dieter MZ, et al. Free Radic Biol Med. 2003 Aug 15;35(4):351-67. doi: 10.1016/s0891-5849(03)00273-9. Free Radic Biol Med. 2003. PMID: 12899938

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