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Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Palmer DC, Webber BR, Patel Y, Johnson MJ, Kariya CM, Lahr WS, Parkhurst MR, Gartner JJ, Prickett TD, Lowery FJ, Kishton RJ, Gurusamy D, Franco Z, Vodnala SK, Diers MD, Wolf NK, Slipek NJ, McKenna DH, Sumstad D, Viney L, Henley T, Bürckstümmer T, Baker O, Hu Y, Yan C, Meerzaman D, Padhan K, Lo W, Malekzadeh P, Jia L, Deniger DC, Patel SJ, Robbins PF, McIvor RS, Choudhry M, Rosenberg SA, Moriarity BS, Restifo NP. Palmer DC, et al. Among authors: diers md. Med. 2022 Oct 14;3(10):682-704.e8. doi: 10.1016/j.medj.2022.07.008. Epub 2022 Aug 24. Med. 2022. PMID: 36007524 Free PMC article.
Author Correction: Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.
Webber BR, Lonetree CL, Kluesner MG, Johnson MJ, Pomeroy EJ, Diers MD, Lahr WS, Draper GM, Slipek NJ, Smeester BA, Lovendahl KN, McElroy AN, Gordon WR, Osborn MJ, Moriarity BS. Webber BR, et al. Among authors: diers md. Nat Commun. 2019 Dec 6;10(1):5659. doi: 10.1038/s41467-019-13778-y. Nat Commun. 2019. PMID: 31811147 Free PMC article.
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair.
Webber BR, Johnson MJ, Skeate JG, Slipek NJ, Lahr WS, DeFeo AP, Mills LJ, Qiu X, Rathmann B, Diers MD, Wick B, Henley T, Choudhry M, Starr TK, McIvor RS, Moriarity BS. Webber BR, et al. Among authors: diers md. Nat Biomed Eng. 2023 Dec 13. doi: 10.1038/s41551-023-01157-4. Online ahead of print. Nat Biomed Eng. 2023. PMID: 38092857
Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality.
Collier LS, Adams DJ, Hackett CS, Bendzick LE, Akagi K, Davies MN, Diers MD, Rodriguez FJ, Bender AM, Tieu C, Matise I, Dupuy AJ, Copeland NG, Jenkins NA, Hodgson JG, Weiss WA, Jenkins RB, Largaespada DA. Collier LS, et al. Among authors: diers md. Cancer Res. 2009 Nov 1;69(21):8429-37. doi: 10.1158/0008-5472.CAN-09-1760. Epub 2009 Oct 20. Cancer Res. 2009. PMID: 19843846 Free PMC article.
18 results