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Combination of Lenvatinib and Pembrolizumab Is an Effective Treatment Option for Anaplastic and Poorly Differentiated Thyroid Carcinoma.
Dierks C, Seufert J, Aumann K, Ruf J, Klein C, Kiefer S, Rassner M, Boerries M, Zielke A, la Rosee P, Meyer PT, Kroiss M, Weißenberger C, Schumacher T, Metzger P, Weiss H, Smaxwil C, Laubner K, Duyster J, von Bubnoff N, Miething C, Thomusch O. Dierks C, et al. Thyroid. 2021 Jul;31(7):1076-1085. doi: 10.1089/thy.2020.0322. Epub 2021 Apr 15. Thyroid. 2021. PMID: 33509020 Free PMC article.
Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression.
Klein C, Zwick A, Kissel S, Forster CU, Pfeifer D, Follo M, Illert AL, Decker S, Benkler T, Pahl H, Oostendorp RA, Aumann K, Duyster J, Dierks C. Klein C, et al. Among authors: dierks c. J Exp Med. 2016 Feb 8;213(2):273-90. doi: 10.1084/jem.20150556. Epub 2016 Feb 1. J Exp Med. 2016. PMID: 26834157 Free PMC article.
Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.
Prestipino A, Emhardt AJ, Aumann K, O'Sullivan D, Gorantla SP, Duquesne S, Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M, Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R. Prestipino A, et al. Among authors: dierks c. Sci Transl Med. 2018 Feb 21;10(429):eaam7729. doi: 10.1126/scitranslmed.aam7729. Sci Transl Med. 2018. PMID: 29467301 Free PMC article.
PIM1 inhibition effectively enhances plerixafor-induced HSC mobilization by counteracting CXCR4 upregulation and blocking CXCL12 secretion.
Müller TA, Pennisi S, Zwick A, Decker S, Klein C, Rister B, Rudorf A, Kissel S, Follo M, Wäsch R, Illert AL, Pfeifer D, Oostendorp R, Waskow C, Dierks C, Duyster J. Müller TA, et al. Among authors: dierks c. Leukemia. 2019 May;33(5):1296-1301. doi: 10.1038/s41375-019-0428-6. Epub 2019 Feb 28. Leukemia. 2019. PMID: 30816332 No abstract available.
Loss of the Fanconi anemia-associated protein NIPA causes bone marrow failure.
Kreutmair S, Erlacher M, Andrieux G, Istvanffy R, Mueller-Rudorf A, Zwick M, Rückert T, Pantic M, Poggio T, Shoumariyeh K, Mueller TA, Kawaguchi H, Follo M, Klingeberg C, Wlodarski M, Baumann I, Pfeifer D, Kulinski M, Rudelius M, Lemeer S, Kuster B, Dierks C, Peschel C, Cabezas-Wallscheid N, Duque-Afonso J, Zeiser R, Cleary ML, Schindler D, Schmitt-Graeff A, Boerries M, Niemeyer CM, Oostendorp RA, Duyster J, Illert AL. Kreutmair S, et al. Among authors: dierks c. J Clin Invest. 2020 Jun 1;130(6):2827-2844. doi: 10.1172/JCI126215. J Clin Invest. 2020. PMID: 32338640 Free PMC article.
Personalized Clinical Decision Making Through Implementation of a Molecular Tumor Board: A German Single-Center Experience.
Hoefflin R, Geißler AL, Fritsch R, Claus R, Wehrle J, Metzger P, Reiser M, Mehmed L, Fauth L, Heiland DH, Erbes T, Stock F, Csanadi A, Miething C, Weddeling B, Meiss F, von Bubnoff D, Dierks C, Ge I, Brass V, Heeg S, Schäfer H, Boeker M, Rawluk J, Botzenhart EM, Kayser G, Hettmer S, Busch H, Peters C, Werner M, Duyster J, Brummer T, Boerries M, Lassmann S, von Bubnoff N. Hoefflin R, et al. Among authors: dierks c. JCO Precis Oncol. 2018 Aug 16;2:PO.18.00105. doi: 10.1200/PO.18.00105. eCollection 2018. JCO Precis Oncol. 2018. PMID: 32913998 Free PMC article.
Questions and Controversies in the Clinical Application of Tyrosine Kinase Inhibitors to Treat Patients with Radioiodine-Refractory Differentiated Thyroid Carcinoma: Expert Perspectives.
Verburg FA, Amthauer H, Binse I, Brink I, Buck A, Darr A, Dierks C, Koch C, König U, Kreissl MC, Luster M, Reuter C, Scheidhauer K, Willenberg HS, Zielke A, Schott M. Verburg FA, et al. Among authors: dierks c. Horm Metab Res. 2021 Mar;53(3):149-160. doi: 10.1055/a-1380-4154. Epub 2021 Mar 2. Horm Metab Res. 2021. PMID: 33652491 Free PMC article. Review.
114 results