Diehl JA - Search Results

1

Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.

Wong GS, Zhou J, Liu JB, Wu Z, Xu X, Li T, Xu D, Schumacher SE, Puschhof J, McFarland J, Zou C, Dulak A, Henderson L, Xu P, O'Day E, Rendak R, Liao WL, Cecchi F, Hembrough T, Schwartz S, Szeto C, Rustgi AK, Wong KK, Diehl JA, Jensen K, Graziano F, Ruzzo A, Fereshetian S, Mertins P, Carr SA, Beroukhim R, Nakamura K, Oki E, Watanabe M, Baba H, Imamura Y, Catenacci D, Bass AJ. Wong GS, et al. Among authors: diehl ja. Nat Med. 2018 Jul;24(7):968-977. doi: 10.1038/s41591-018-0022-x. Epub 2018 May 28. Nat Med. 2018. PMID: 29808010 Free PMC article.

2

Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1.

Benzeno S, Lu F, Guo M, Barbash O, Zhang F, Herman JG, Klein PS, Rustgi A, Diehl JA. Benzeno S, et al. Among authors: diehl ja. Oncogene. 2006 Oct 12;25(47):6291-303. doi: 10.1038/sj.onc.1209644. Epub 2006 May 29. Oncogene. 2006. PMID: 16732330

3

AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture.

Oyama K, Okawa T, Nakagawa H, Takaoka M, Andl CD, Kim SH, Klein-Szanto A, Diehl JA, Herlyn M, El-Deiry W, Rustgi AK. Oyama K, et al. Among authors: diehl ja. Oncogene. 2007 Apr 5;26(16):2353-64. doi: 10.1038/sj.onc.1210025. Epub 2006 Oct 9. Oncogene. 2007. PMID: 17043653 Free PMC article.

4

Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation.

Plastaras JP, Kim SH, Liu YY, Dicker DT, Dorsey JF, McDonough J, Cerniglia G, Rajendran RR, Gupta A, Rustgi AK, Diehl JA, Smith CD, Flaherty KT, El-Deiry WS. Plastaras JP, et al. Among authors: diehl ja. Cancer Res. 2007 Oct 1;67(19):9443-54. doi: 10.1158/0008-5472.CAN-07-1473. Cancer Res. 2007. PMID: 17909054

5

Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication.

Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, Goradia A, Wasik MA, Klein-Szanto AJ, Rustgi AK, Bassing CH, Diehl JA. Aggarwal P, et al. Among authors: diehl ja. Genes Dev. 2007 Nov 15;21(22):2908-22. doi: 10.1101/gad.1586007. Genes Dev. 2007. PMID: 18006686 Free PMC article.

6

Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer.

Barbash O, Zamfirova P, Lin DI, Chen X, Yang K, Nakagawa H, Lu F, Rustgi AK, Diehl JA. Barbash O, et al. Among authors: diehl ja. Cancer Cell. 2008 Jul 8;14(1):68-78. doi: 10.1016/j.ccr.2008.05.017. Cancer Cell. 2008. PMID: 18598945 Free PMC article.

7

Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway.

Lioni M, Noma K, Snyder A, Klein-Szanto A, Diehl JA, Rustgi AK, Herlyn M, Smalley KS. Lioni M, et al. Among authors: diehl ja. Mol Cancer Ther. 2008 Sep;7(9):2866-75. doi: 10.1158/1535-7163.MCT-08-0391. Mol Cancer Ther. 2008. PMID: 18790767 Free PMC article.

8

Cleavage of MCM2 licensing protein fosters senescence in human keratinocytes.

Harada H, Nakagawa H, Takaoka M, Lee J, Herlyn M, Diehl JA, Rustgi AK. Harada H, et al. Among authors: diehl ja. Cell Cycle. 2008 Nov 15;7(22):3534-8. doi: 10.4161/cc.7.22.7043. Epub 2008 Nov 18. Cell Cycle. 2008. PMID: 19001876 Free PMC article.

9

A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification.

Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK. Kalabis J, et al. Among authors: diehl ja. J Clin Invest. 2008 Dec;118(12):3860-9. doi: 10.1172/JCI35012. Epub 2008 Nov 6. J Clin Invest. 2008. PMID: 19033657 Free PMC article.

10

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.

Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA, Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK, Nakagawa H. Ohashi S, et al. Among authors: diehl ja. Cancer Res. 2010 May 15;70(10):4174-84. doi: 10.1158/0008-5472.CAN-09-4614. Epub 2010 Apr 27. Cancer Res. 2010. PMID: 20424117 Free PMC article.

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