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Rescue of glutaric aciduria type I in mice by liver-directed therapies.
Barzi M, Johnson CG, Chen T, Rodriguiz RM, Hemmingsen M, Gonzalez TJ, Rosales A, Beasley J, Peck CK, Ma Y, Stiles AR, Wood TC, Maeso-Diaz R, Diehl AM, Young SP, Everitt JI, Wetsel WC, Lagor WR, Bissig-Choisat B, Asokan A, El-Gharbawy A, Bissig KD. Barzi M, et al. Among authors: diehl am. Sci Transl Med. 2023 Apr 19;15(692):eadf4086. doi: 10.1126/scitranslmed.adf4086. Epub 2023 Apr 19. Sci Transl Med. 2023. PMID: 37075130 Free PMC article.
Aging reduces liver resiliency by dysregulating Hedgehog signaling.
Maeso-Díaz R, Dalton GD, Oh S, Du K, Tang L, Chen T, Dutta RK, Hartman JH, Meyer JN, Diehl AM. Maeso-Díaz R, et al. Among authors: diehl am. Aging Cell. 2022 Feb;21(2):e13530. doi: 10.1111/acel.13530. Epub 2022 Jan 4. Aging Cell. 2022. PMID: 34984806 Free PMC article.
A humanized mouse model for adeno-associated viral gene therapy.
Barzi M, Chen T, Gonzalez TJ, Pankowicz FP, Oh SH, Streff HL, Rosales A, Ma Y, Collias S, Woodfield SE, Diehl AM, Vasudevan SA, Galvan TN, Goss J, Gersbach CA, Bissig-Choisat B, Asokan A, Bissig KD. Barzi M, et al. Among authors: diehl am. Nat Commun. 2024 Mar 4;15(1):1955. doi: 10.1038/s41467-024-46017-0. Nat Commun. 2024. PMID: 38438373 Free PMC article.
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.
Zhu C, Kim K, Wang X, Bartolome A, Salomao M, Dongiovanni P, Meroni M, Graham MJ, Yates KP, Diehl AM, Schwabe RF, Tabas I, Valenti L, Lavine JE, Pajvani UB. Zhu C, et al. Among authors: diehl am. Sci Transl Med. 2018 Nov 21;10(468):eaat0344. doi: 10.1126/scitranslmed.aat0344. Sci Transl Med. 2018. PMID: 30463916 Free PMC article.
Hedgehog signaling in the liver.
Omenetti A, Choi S, Michelotti G, Diehl AM. Omenetti A, et al. Among authors: diehl am. J Hepatol. 2011 Feb;54(2):366-73. doi: 10.1016/j.jhep.2010.10.003. Epub 2010 Oct 14. J Hepatol. 2011. PMID: 21093090 Free PMC article. Review.
497 results