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Aging reduces liver resiliency by dysregulating Hedgehog signaling.
Maeso-Díaz R, Dalton GD, Oh S, Du K, Tang L, Chen T, Dutta RK, Hartman JH, Meyer JN, Diehl AM. Maeso-Díaz R, et al. Among authors: diehl am. Aging Cell. 2022 Feb;21(2):e13530. doi: 10.1111/acel.13530. Epub 2022 Jan 4. Aging Cell. 2022. PMID: 34984806 Free PMC article.
Role for hedgehog signaling in hepatic stellate cell activation and viability.
Sicklick JK, Li YX, Choi SS, Qi Y, Chen W, Bustamante M, Huang J, Zdanowicz M, Camp T, Torbenson MS, Rojkind M, Diehl AM. Sicklick JK, et al. Among authors: diehl am. Lab Invest. 2005 Nov;85(11):1368-80. doi: 10.1038/labinvest.3700349. Lab Invest. 2005. PMID: 16170335 Free article.
Hedgehog signaling maintains resident hepatic progenitors throughout life.
Sicklick JK, Li YX, Melhem A, Schmelzer E, Zdanowicz M, Huang J, Caballero M, Fair JH, Ludlow JW, McClelland RE, Reid LM, Diehl AM. Sicklick JK, et al. Among authors: diehl am. Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G859-70. doi: 10.1152/ajpgi.00456.2005. Epub 2005 Dec 1. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16322088 Free article.
497 results