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Native metabolomics identifies the rivulariapeptolide family of protease inhibitors.
Reher R, Aron AT, Fajtová P, Stincone P, Wagner B, Pérez-Lorente AI, Liu C, Shalom IYB, Bittremieux W, Wang M, Jeong K, Matos-Hernandez ML, Alexander KL, Caro-Diaz EJ, Naman CB, Scanlan JHW, Hochban PMM, Diederich WE, Molina-Santiago C, Romero D, Selim KA, Sass P, Brötz-Oesterhelt H, Hughes CC, Dorrestein PC, O'Donoghue AJ, Gerwick WH, Petras D. Reher R, et al. Among authors: diederich we. Nat Commun. 2022 Aug 8;13(1):4619. doi: 10.1038/s41467-022-32016-6. Nat Commun. 2022. PMID: 35941113 Free PMC article.
RNase P Inhibitors Identified as Aggregators.
Schencking I, Schäfer EM, Scanlan JHW, Wenzel BM, Emmerich RE, Steinmetzer T, Diederich WE, Schlitzer M, Hartmann RK. Schencking I, et al. Among authors: diederich we. Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0030021. doi: 10.1128/AAC.00300-21. Epub 2021 Jul 16. Antimicrob Agents Chemother. 2021. PMID: 33972249 Free PMC article.
One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists.
Schiebel J, Radeva N, Köster H, Metz A, Krotzky T, Kuhnert M, Diederich WE, Heine A, Neumann L, Atmanene C, Roecklin D, Vivat-Hannah V, Renaud JP, Meinecke R, Schlinck N, Sitte A, Popp F, Zeeb M, Klebe G. Schiebel J, et al. Among authors: diederich we. ChemMedChem. 2015 Sep;10(9):1511-21. doi: 10.1002/cmdc.201500267. Epub 2015 Aug 10. ChemMedChem. 2015. PMID: 26259992
Novel dengue virus NS2B/NS3 protease inhibitors.
Wu H, Bock S, Snitko M, Berger T, Weidner T, Holloway S, Kanitz M, Diederich WE, Steuber H, Walter C, Hofmann D, Weißbrich B, Spannaus R, Acosta EG, Bartenschlager R, Engels B, Schirmeister T, Bodem J. Wu H, et al. Among authors: diederich we. Antimicrob Agents Chemother. 2015 Feb;59(2):1100-9. doi: 10.1128/AAC.03543-14. Epub 2014 Dec 8. Antimicrob Agents Chemother. 2015. PMID: 25487800 Free PMC article.
54 results