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Page 1
An abundant dysfunctional apolipoprotein A1 in human atheroma.
Huang Y, DiDonato JA, Levison BS, Schmitt D, Li L, Wu Y, Buffa J, Kim T, Gerstenecker GS, Gu X, Kadiyala CS, Wang Z, Culley MK, Hazen JE, Didonato AJ, Fu X, Berisha SZ, Peng D, Nguyen TT, Liang S, Chuang CC, Cho L, Plow EF, Fox PL, Gogonea V, Tang WH, Parks JS, Fisher EA, Smith JD, Hazen SL. Huang Y, et al. Among authors: didonato aj. Nat Med. 2014 Feb;20(2):193-203. doi: 10.1038/nm.3459. Epub 2014 Jan 26. Nat Med. 2014. PMID: 24464187 Free PMC article.
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex.
Huang Y, Wu Z, Riwanto M, Gao S, Levison BS, Gu X, Fu X, Wagner MA, Besler C, Gerstenecker G, Zhang R, Li XM, DiDonato AJ, Gogonea V, Tang WH, Smith JD, Plow EF, Fox PL, Shih DM, Lusis AJ, Fisher EA, DiDonato JA, Landmesser U, Hazen SL. Huang Y, et al. Among authors: didonato aj. J Clin Invest. 2013 Sep;123(9):3815-28. doi: 10.1172/JCI67478. Epub 2013 Aug 1. J Clin Invest. 2013. PMID: 23908111 Free PMC article.
Site-specific nitration of apolipoprotein A-I at tyrosine 166 is both abundant within human atherosclerotic plaque and dysfunctional.
DiDonato JA, Aulak K, Huang Y, Wagner M, Gerstenecker G, Topbas C, Gogonea V, DiDonato AJ, Tang WHW, Mehl RA, Fox PL, Plow EF, Smith JD, Fisher EA, Hazen SL. DiDonato JA, et al. Among authors: didonato aj. J Biol Chem. 2014 Apr 11;289(15):10276-10292. doi: 10.1074/jbc.M114.556506. Epub 2014 Feb 20. J Biol Chem. 2014. PMID: 24558038 Free PMC article.
A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein.
Gu X, Wu Z, Huang Y, Wagner MA, Baleanu-Gogonea C, Mehl RA, Buffa JA, DiDonato AJ, Hazen LB, Fox PL, Gogonea V, Parks JS, DiDonato JA, Hazen SL. Gu X, et al. Among authors: didonato aj. J Biol Chem. 2016 Mar 18;291(12):6386-95. doi: 10.1074/jbc.M115.696088. Epub 2016 Jan 21. J Biol Chem. 2016. PMID: 26797122 Free PMC article.
Site-specific 5-hydroxytryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high-density lipoprotein biogenesis.
Zamanian-Daryoush M, Gogonea V, DiDonato AJ, Buffa JA, Choucair I, Levison BS, Hughes RA, Ellington AD, Huang Y, Li XS, DiDonato JA, Hazen SL. Zamanian-Daryoush M, et al. Among authors: didonato aj. J Biol Chem. 2020 Apr 10;295(15):4836-4848. doi: 10.1074/jbc.RA119.012092. Epub 2020 Feb 25. J Biol Chem. 2020. PMID: 32098873 Free PMC article.
Gut microbes impact stroke severity via the trimethylamine N-oxide pathway.
Zhu W, Romano KA, Li L, Buffa JA, Sangwan N, Prakash P, Tittle AN, Li XS, Fu X, Androjna C, DiDonato AJ, Brinson K, Trapp BD, Fischbach MA, Rey FE, Hajjar AM, DiDonato JA, Hazen SL. Zhu W, et al. Among authors: didonato aj. Cell Host Microbe. 2021 Jul 14;29(7):1199-1208.e5. doi: 10.1016/j.chom.2021.05.002. Epub 2021 Jun 16. Cell Host Microbe. 2021. PMID: 34139173 Free PMC article.
Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia.
Davuluri G, Giusto M, Chandel R, Welch N, Alsabbagh K, Kant S, Kumar A, Kim A, Gangadhariah M, Ghosh PK, Tran U, Krajcik DM, Vasu K, DiDonato AJ, DiDonato JA, Willard B, Monga SP, Wang Y, Fox PL, Stark GR, Wessely O, Esser KA, Dasarathy S. Davuluri G, et al. Among authors: didonato aj. Mol Cell Biol. 2019 Jul 29;39(16):e00451-18. doi: 10.1128/MCB.00451-18. Print 2019 Aug 15. Mol Cell Biol. 2019. PMID: 31138664 Free PMC article.