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Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy.
Min Y, Wang X, İş Ö, Patel TA, Gao J, Reddy JS, Quicksall ZS, Nguyen T, Lin S, Tutor-New FQ, Chalk JL, Mitchell AO, Crook JE, Nelson PT, Van Eldik LJ, Golde TE, Carrasquillo MM, Dickson DW, Zhang K, Allen M, Ertekin-Taner N. Min Y, et al. Among authors: dickson dw. Nat Commun. 2023 Nov 2;14(1):6801. doi: 10.1038/s41467-023-42626-3. Nat Commun. 2023. PMID: 37919278 Free PMC article.
Abeta40 inhibits amyloid deposition in vivo.
Kim J, Onstead L, Randle S, Price R, Smithson L, Zwizinski C, Dickson DW, Golde T, McGowan E. Kim J, et al. Among authors: dickson dw. J Neurosci. 2007 Jan 17;27(3):627-33. doi: 10.1523/JNEUROSCI.4849-06.2007. J Neurosci. 2007. PMID: 17234594 Free PMC article.
Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease.
Zou F, Gopalraj RK, Lok J, Zhu H, Ling IF, Simpson JF, Tucker HM, Kelly JF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Bennett DA, Crook JE, Younkin SG, Estus S. Zou F, et al. Among authors: dickson dw. Hum Mol Genet. 2008 Apr 1;17(7):929-35. doi: 10.1093/hmg/ddm365. Epub 2007 Dec 8. Hum Mol Genet. 2008. PMID: 18065781 Free PMC article.
Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.
Carrasquillo MM, Zou F, Pankratz VS, Wilcox SL, Ma L, Walker LP, Younkin SG, Younkin CS, Younkin LH, Bisceglio GD, Ertekin-Taner N, Crook JE, Dickson DW, Petersen RC, Graff-Radford NR, Younkin SG. Carrasquillo MM, et al. Among authors: dickson dw. Nat Genet. 2009 Feb;41(2):192-8. doi: 10.1038/ng.305. Epub 2009 Jan 11. Nat Genet. 2009. PMID: 19136949 Free PMC article.
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity.
Zhang YJ, Xu YF, Cook C, Gendron TF, Roettges P, Link CD, Lin WL, Tong J, Castanedes-Casey M, Ash P, Gass J, Rangachari V, Buratti E, Baralle F, Golde TE, Dickson DW, Petrucelli L. Zhang YJ, et al. Among authors: dickson dw. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7607-12. doi: 10.1073/pnas.0900688106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383787 Free PMC article.
Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease.
Carrasquillo MM, Belbin O, Zou F, Allen M, Ertekin-Taner N, Ansari M, Wilcox SL, Kashino MR, Ma L, Younkin LH, Younkin SG, Younkin CS, Dincman TA, Howard ME, Howell CC, Stanton CM, Watson CM, Crump M, Vitart V, Hayward C, Hastie ND, Rudan I, Campbell H, Polasek O, Brown K, Passmore P, Craig D, McGuinness B, Todd S, Kehoe PG, Mann DM, Smith AD, Beaumont H, Warden D, Holmes C, Heun R, Kölsch H, Kalsheker N, Pankratz VS, Dickson DW, Graff-Radford NR, Petersen RC, Wright AF, Younkin SG, Morgan K. Carrasquillo MM, et al. Among authors: dickson dw. PLoS One. 2010 Jan 19;5(1):e8764. doi: 10.1371/journal.pone.0008764. PLoS One. 2010. PMID: 20098734 Free PMC article.
1,314 results