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Target-induced clustering activates Trim-Away of pathogens and proteins.
Zeng J, Santos AF, Mukadam AS, Osswald M, Jacques DA, Dickson CF, McLaughlin SH, Johnson CM, Kiss L, Luptak J, Renner N, Vaysburd M, McEwan WA, Morais-de-Sá E, Clift D, James LC. Zeng J, et al. Among authors: dickson cf. Nat Struct Mol Biol. 2021 Mar;28(3):278-289. doi: 10.1038/s41594-021-00560-2. Epub 2021 Feb 25. Nat Struct Mol Biol. 2021. PMID: 33633400 Free PMC article.
Evasion of cGAS and TRIM5 defines pandemic HIV.
Zuliani-Alvarez L, Govasli ML, Rasaiyaah J, Monit C, Perry SO, Sumner RP, McAlpine-Scott S, Dickson C, Rifat Faysal KM, Hilditch L, Miles RJ, Bibollet-Ruche F, Hahn BH, Boecking T, Pinotsis N, James LC, Jacques DA, Towers GJ. Zuliani-Alvarez L, et al. Nat Microbiol. 2022 Nov;7(11):1762-1776. doi: 10.1038/s41564-022-01247-0. Epub 2022 Oct 26. Nat Microbiol. 2022. PMID: 36289397 Free PMC article.
The HIV capsid mimics karyopherin engagement of FG-nucleoporins.
Dickson CF, Hertel S, Tuckwell AJ, Li N, Ruan J, Al-Izzi SC, Ariotti N, Sierecki E, Gambin Y, Morris RG, Towers GJ, Böcking T, Jacques DA. Dickson CF, et al. Nature. 2024 Feb;626(8000):836-842. doi: 10.1038/s41586-023-06969-7. Epub 2024 Jan 24. Nature. 2024. PMID: 38267582 Free PMC article.
Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH.
Krishna Kumar K, Jacques DA, Pishchany G, Caradoc-Davies T, Spirig T, Malmirchegini GR, Langley DB, Dickson CF, Mackay JP, Clubb RT, Skaar EP, Guss JM, Gell DA. Krishna Kumar K, et al. Among authors: dickson cf. J Biol Chem. 2011 Nov 4;286(44):38439-38447. doi: 10.1074/jbc.M111.287300. Epub 2011 Sep 14. J Biol Chem. 2011. PMID: 21917915 Free PMC article.
23 results