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Ketolysis drives CD8+ T cell effector function through effects on histone acetylation.
Luda KM, Longo J, Kitchen-Goosen SM, Duimstra LR, Ma EH, Watson MJ, Oswald BM, Fu Z, Madaj Z, Kupai A, Dickson BM, DeCamp LM, Dahabieh MS, Compton SE, Teis R, Kaymak I, Lau KH, Kelly DP, Puchalska P, Williams KS, Krawczyk CM, Lévesque D, Boisvert FM, Sheldon RD, Rothbart SB, Crawford PA, Jones RG. Luda KM, et al. Among authors: dickson bm. Immunity. 2023 Sep 12;56(9):2021-2035.e8. doi: 10.1016/j.immuni.2023.07.002. Epub 2023 Jul 28. Immunity. 2023. PMID: 37516105 Free article.
UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation.
Tiedemann RL, Hrit J, Du Q, Wiseman AK, Eden HE, Dickson BM, Kong X, Chomiak AA, Vaughan RM, Hebert JM, David Y, Zhou W, Baylin SB, Jones PA, Clark SJ, Rothbart SB. Tiedemann RL, et al. Among authors: dickson bm. bioRxiv [Preprint]. 2024 Feb 16:2024.02.13.580169. doi: 10.1101/2024.02.13.580169. bioRxiv. 2024. PMID: 38405904 Free PMC article. Preprint.
The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.
Vaughan RM, Kupai A, Foley CA, Sagum CA, Tibben BM, Eden HE, Tiedemann RL, Berryhill CA, Patel V, Shaw KM, Krajewski K, Strahl BD, Bedford MT, Frye SV, Dickson BM, Rothbart SB. Vaughan RM, et al. Among authors: dickson bm. Epigenetics Chromatin. 2020 Oct 23;13(1):44. doi: 10.1186/s13072-020-00366-4. Epigenetics Chromatin. 2020. PMID: 33097091 Free PMC article.
A physical basis for quantitative ChIP-sequencing.
Dickson BM, Tiedemann RL, Chomiak AA, Cornett EM, Vaughan RM, Rothbart SB. Dickson BM, et al. J Biol Chem. 2020 Nov 20;295(47):15826-15837. doi: 10.1074/jbc.RA120.015353. Epub 2020 Sep 29. J Biol Chem. 2020. PMID: 32994221 Free PMC article.
48 results