Dick T - Search Results

1

Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance.

Lan T, Ganapathy US, Sharma S, Ahn YM, Zimmerman M, Molodtsov V, Hegde P, Gengenbacher M, Ebright RH, Dartois V, Freundlich JS, Dick T, Aldrich CC. Lan T, et al. Among authors: dick t. Angew Chem Int Ed Engl. 2022 Nov 7;61(45):e202211498. doi: 10.1002/anie.202211498. Epub 2022 Oct 12. Angew Chem Int Ed Engl. 2022. PMID: 36222275 Free PMC article.

2

Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability.

Gengenbacher M, Rao SPS, Pethe K, Dick T. Gengenbacher M, et al. Among authors: dick t. Microbiology (Reading). 2010 Jan;156(Pt 1):81-87. doi: 10.1099/mic.0.033084-0. Epub 2009 Oct 1. Microbiology (Reading). 2010. PMID: 19797356 Free article.

3

Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis.

Dick T, Manjunatha U, Kappes B, Gengenbacher M. Dick T, et al. Mol Microbiol. 2010 Nov;78(4):980-8. doi: 10.1111/j.1365-2958.2010.07381.x. Epub 2010 Sep 22. Mol Microbiol. 2010. PMID: 20815826 Free article.

4

Reduced drug uptake in phenotypically resistant nutrient-starved nonreplicating Mycobacterium tuberculosis.

Sarathy J, Dartois V, Dick T, Gengenbacher M. Sarathy J, et al. Among authors: dick t. Antimicrob Agents Chemother. 2013 Apr;57(4):1648-53. doi: 10.1128/AAC.02202-12. Epub 2013 Jan 18. Antimicrob Agents Chemother. 2013. PMID: 23335744 Free PMC article.

5

Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents.

Lakshminarayana SB, Huat TB, Ho PC, Manjunatha UH, Dartois V, Dick T, Rao SP. Lakshminarayana SB, et al. Among authors: dick t. J Antimicrob Chemother. 2015 Mar;70(3):857-67. doi: 10.1093/jac/dku457. Epub 2014 Nov 11. J Antimicrob Chemother. 2015. PMID: 25587994 Free PMC article.

6

Antibacterial drug discovery: doing it right.

Gengenbacher M, Dick T. Gengenbacher M, et al. Among authors: dick t. Chem Biol. 2015 Jan 22;22(1):5-6. doi: 10.1016/j.chembiol.2014.12.005. Chem Biol. 2015. PMID: 25615950

7

Mild Nutrient Starvation Triggers the Development of a Small-Cell Survival Morphotype in Mycobacteria.

Wu ML, Gengenbacher M, Dick T. Wu ML, et al. Among authors: dick t. Front Microbiol. 2016 Jun 16;7:947. doi: 10.3389/fmicb.2016.00947. eCollection 2016. Front Microbiol. 2016. PMID: 27379076 Free PMC article.

8

Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis.

Gopal P, Yee M, Sarathy J, Low JL, Sarathy JP, Kaya F, Dartois V, Gengenbacher M, Dick T. Gopal P, et al. Among authors: dick t. ACS Infect Dis. 2016 Sep 9;2(9):616-626. doi: 10.1021/acsinfecdis.6b00070. Epub 2016 Aug 8. ACS Infect Dis. 2016. PMID: 27759369 Free PMC article.

9

Developmental transcriptome of resting cell formation in Mycobacterium smegmatis.

Wu ML, Gengenbacher M, Chung JC, Chen SL, Mollenkopf HJ, Kaufmann SH, Dick T. Wu ML, et al. Among authors: dick t. BMC Genomics. 2016 Oct 26;17(1):837. doi: 10.1186/s12864-016-3190-4. BMC Genomics. 2016. PMID: 27784279 Free PMC article.

10

Rifabutin Is Active against Mycobacterium abscessus Complex.

Aziz DB, Low JL, Wu ML, Gengenbacher M, Teo JWP, Dartois V, Dick T. Aziz DB, et al. Among authors: dick t. Antimicrob Agents Chemother. 2017 May 24;61(6):e00155-17. doi: 10.1128/AAC.00155-17. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28396540 Free PMC article.

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