Dick T - Search Results

1

Discovery of a Novel Mycobacterial F-ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines.

Hotra A, Ragunathan P, Ng PS, Seankongsuk P, Harikishore A, Sarathy JP, Saw WG, Lakshmanan U, Sae-Lao P, Kalia NP, Shin J, Kalyanasundaram R, Anbarasu S, Parthasarathy K, Pradeep CN, Makhija H, Dröge P, Poulsen A, Tan JHL, Pethe K, Dick T, Bates RW, Grüber G. Hotra A, et al. Among authors: dick t. Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13295-13304. doi: 10.1002/anie.202002546. Epub 2020 May 26. Angew Chem Int Ed Engl. 2020. PMID: 32337801

2

Sensitive profiling of chemically diverse bioactive lipids.

Shui G, Bendt AK, Pethe K, Dick T, Wenk MR. Shui G, et al. Among authors: dick t. J Lipid Res. 2007 Sep;48(9):1976-84. doi: 10.1194/jlr.M700060-JLR200. Epub 2007 Jun 12. J Lipid Res. 2007. PMID: 17565170 Free article.

3

Recombinase-based reporter system and antisense technology to study gene expression and essentiality in hypoxic nonreplicating mycobacteria.

Rao SP, Camacho L, Huat Tan B, Boon C, Russel DG, Dick T, Pethe K. Rao SP, et al. Among authors: dick t. FEMS Microbiol Lett. 2008 Jul;284(1):68-75. doi: 10.1111/j.1574-6968.2008.01193.x. FEMS Microbiol Lett. 2008. PMID: 18544099

4

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis.

Rao SP, Alonso S, Rand L, Dick T, Pethe K. Rao SP, et al. Among authors: dick t. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11945-50. doi: 10.1073/pnas.0711697105. Epub 2008 Aug 12. Proc Natl Acad Sci U S A. 2008. PMID: 18697942 Free PMC article.

5

Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin.

Low KL, Rao PS, Shui G, Bendt AK, Pethe K, Dick T, Wenk MR. Low KL, et al. Among authors: dick t. J Bacteriol. 2009 Aug;191(16):5037-43. doi: 10.1128/JB.00530-09. Epub 2009 Jun 12. J Bacteriol. 2009. PMID: 19525349 Free PMC article.

6

Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability.

Gengenbacher M, Rao SPS, Pethe K, Dick T. Gengenbacher M, et al. Among authors: dick t. Microbiology (Reading). 2010 Jan;156(Pt 1):81-87. doi: 10.1099/mic.0.033084-0. Epub 2009 Oct 1. Microbiology (Reading). 2010. PMID: 19797356 Free article.

7

Variations of subunit {varepsilon} of the Mycobacterium tuberculosis F1Fo ATP synthase and a novel model for mechanism of action of the tuberculosis drug TMC207.

Biukovic G, Basak S, Manimekalai MS, Rishikesan S, Roessle M, Dick T, Rao SP, Hunke C, Grüber G. Biukovic G, et al. Among authors: dick t. Antimicrob Agents Chemother. 2013 Jan;57(1):168-76. doi: 10.1128/AAC.01039-12. Epub 2012 Oct 22. Antimicrob Agents Chemother. 2013. PMID: 23089752 Free PMC article.

8

Characterization of phosphofructokinase activity in Mycobacterium tuberculosis reveals that a functional glycolytic carbon flow is necessary to limit the accumulation of toxic metabolic intermediates under hypoxia.

Phong WY, Lin W, Rao SP, Dick T, Alonso S, Pethe K. Phong WY, et al. Among authors: dick t. PLoS One. 2013;8(2):e56037. doi: 10.1371/journal.pone.0056037. Epub 2013 Feb 7. PLoS One. 2013. PMID: 23409118 Free PMC article.

9

para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis.

Zheng J, Rubin EJ, Bifani P, Mathys V, Lim V, Au M, Jang J, Nam J, Dick T, Walker JR, Pethe K, Camacho LR. Zheng J, et al. Among authors: dick t. J Biol Chem. 2013 Aug 9;288(32):23447-56. doi: 10.1074/jbc.M113.475798. Epub 2013 Jun 18. J Biol Chem. 2013. PMID: 23779105 Free PMC article.

10

Reactive dirty fragments: implications for tuberculosis drug discovery.

Gopal P, Dick T. Gopal P, et al. Among authors: dick t. Curr Opin Microbiol. 2014 Oct;21:7-12. doi: 10.1016/j.mib.2014.06.015. Epub 2014 Jul 30. Curr Opin Microbiol. 2014. PMID: 25078318 Free article. Review.

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