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Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes.
Jiang Z, Li H, Schroer SA, Voisin V, Ju Y, Pacal M, Erdmann N, Shi W, Chung PED, Deng T, Chen NJ, Ciavarra G, Datti A, Mak TW, Harrington L, Dick FA, Bader GD, Bremner R, Woo M, Zacksenhaus E. Jiang Z, et al. Among authors: dick fa. EMBO J. 2022 Feb 15;41(4):e106825. doi: 10.15252/embj.2020106825. Epub 2022 Jan 13. EMBO J. 2022. PMID: 35023164 Free PMC article.
The retinoblastoma protein regulates pericentric heterochromatin.
Isaac CE, Francis SM, Martens AL, Julian LM, Seifried LA, Erdmann N, Binné UK, Harrington L, Sicinski P, Bérubé NG, Dyson NJ, Dick FA. Isaac CE, et al. Among authors: dick fa. Mol Cell Biol. 2006 May;26(9):3659-71. doi: 10.1128/MCB.26.9.3659-3671.2006. Mol Cell Biol. 2006. PMID: 16612004 Free PMC article.
A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice.
Cecchini MJ, Thwaites MJ, Talluri S, MacDonald JI, Passos DT, Chong JL, Cantalupo P, Stafford PM, Sáenz-Robles MT, Francis SM, Pipas JM, Leone G, Welch I, Dick FA. Cecchini MJ, et al. Among authors: dick fa. Mol Cell Biol. 2014 Jun;34(11):2029-45. doi: 10.1128/MCB.01589-13. Epub 2014 Mar 24. Mol Cell Biol. 2014. PMID: 24662053 Free PMC article.
Analyzing RB and E2F during the G1-S transition.
Thwaites MJ, Cecchini MJ, Dick FA. Thwaites MJ, et al. Among authors: dick fa. Methods Mol Biol. 2014;1170:449-61. doi: 10.1007/978-1-4939-0888-2_24. Methods Mol Biol. 2014. PMID: 24906329
91 results