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The road ahead for health and lifespan interventions.
Gonzalez-Freire M, Diaz-Ruiz A, Hauser D, Martinez-Romero J, Ferrucci L, Bernier M, de Cabo R. Gonzalez-Freire M, et al. Ageing Res Rev. 2020 May;59:101037. doi: 10.1016/j.arr.2020.101037. Epub 2020 Feb 25. Ageing Res Rev. 2020. PMID: 32109604 Free PMC article. Review.
SIRT1 synchs satellite cell metabolism with stem cell fate.
Diaz-Ruiz A, Gonzalez-Freire M, Ferrucci L, Bernier M, de Cabo R. Diaz-Ruiz A, et al. Cell Stem Cell. 2015 Feb 5;16(2):103-4. doi: 10.1016/j.stem.2015.01.006. Cell Stem Cell. 2015. PMID: 25658362 Free article.
Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation.
Di Francesco A, Di Germanio C, Panda AC, Huynh P, Peaden R, Navas-Enamorado I, Bastian P, Lehrmann E, Diaz-Ruiz A, Ross D, Siegel D, Martindale JL, Bernier M, Gorospe M, Abdelmohsen K, de Cabo R. Di Francesco A, et al. Free Radic Biol Med. 2016 Oct;99:225-233. doi: 10.1016/j.freeradbiomed.2016.08.005. Epub 2016 Aug 8. Free Radic Biol Med. 2016. PMID: 27515817 Free PMC article.
Cytochrome b5 reductase and the control of lipid metabolism and healthspan.
Martin-Montalvo A, Sun Y, Diaz-Ruiz A, Ali A, Gutierrez V, Palacios HH, Curtis J, Siendones E, Ariza J, Abulwerdi GA, Sun X, Wang AX, Pearson KJ, Fishbein KW, Spencer RG, Wang M, Han X, Scheibye-Knudsen M, Baur JA, Shertzer HG, Navas P, Villalba JM, Zou S, Bernier M, de Cabo R. Martin-Montalvo A, et al. NPJ Aging Mech Dis. 2016 May 12;2:16006. doi: 10.1038/npjamd.2016.6. eCollection 2016. NPJ Aging Mech Dis. 2016. PMID: 28721264 Free PMC article.
Hexokinases link DJ-1 to the PINK1/parkin pathway.
Hauser DN, Mamais A, Conti MM, Primiani CT, Kumaran R, Dillman AA, Langston RG, Beilina A, Garcia JH, Diaz-Ruiz A, Bernier M, Fiesel FC, Hou X, Springer W, Li Y, de Cabo R, Cookson MR. Hauser DN, et al. Mol Neurodegener. 2017 Sep 29;12(1):70. doi: 10.1186/s13024-017-0212-x. Mol Neurodegener. 2017. PMID: 28962651 Free PMC article.
Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: The Baltimore Longitudinal Study of Aging.
Gonzalez-Freire M, Scalzo P, D'Agostino J, Moore ZA, Diaz-Ruiz A, Fabbri E, Zane A, Chen B, Becker KG, Lehrmann E, Zukley L, Chia CW, Tanaka T, Coen PM, Bernier M, de Cabo R, Ferrucci L. Gonzalez-Freire M, et al. Aging Cell. 2018 Apr;17(2):e12725. doi: 10.1111/acel.12725. Epub 2018 Jan 21. Aging Cell. 2018. PMID: 29356348 Free PMC article.
Intermittent mTOR Inhibition Reverses Kidney Aging in Old Rats.
Di Francesco A, Diaz-Ruiz A, de Cabo R, Bernier M. Di Francesco A, et al. J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):843-844. doi: 10.1093/gerona/gly023. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29420687 Free PMC article. No abstract available.
Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance.
Price NL, Singh AK, Rotllan N, Goedeke L, Wing A, Canfrán-Duque A, Diaz-Ruiz A, Araldi E, Baldán Á, Camporez JP, Suárez Y, Rodeheffer MS, Shulman GI, de Cabo R, Fernández-Hernando C. Price NL, et al. Cell Rep. 2018 Feb 20;22(8):2133-2145. doi: 10.1016/j.celrep.2018.01.074. Cell Rep. 2018. PMID: 29466739 Free PMC article.
114 results