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Pim-1 kinase is a positive feedback regulator of the senescent lung fibroblast inflammatory secretome.
Gao AY, Diaz Espinosa AM, Gianì F, Pham TX, Carver CM, Aravamudhan A, Bartman CM, Ligresti G, Caporarello N, Schafer MJ, Haak AJ. Gao AY, et al. Among authors: diaz espinosa am. Am J Physiol Lung Cell Mol Physiol. 2022 Dec 1;323(6):L685-L697. doi: 10.1152/ajplung.00023.2022. Epub 2022 Oct 12. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 36223640 Free PMC article.
Combined control of the fibroblast contractile program by YAP and TAZ.
Link PA, Choi KM, Diaz Espinosa AM, Jones DL, Gao AY, Haak AJ, Tschumperlin DJ. Link PA, et al. Among authors: diaz espinosa am. Am J Physiol Lung Cell Mol Physiol. 2022 Jan 1;322(1):L23-L32. doi: 10.1152/ajplung.00210.2021. Epub 2021 Nov 10. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 34755530 Free PMC article.
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation.
Jones DL, Meridew JA, Link PA, Ducharme MT, Lydon KL, Choi KM, Caporarello N, Tan Q, Diaz Espinosa AM, Xiong Y, Lee JH, Ye Z, Yan H, Ordog T, Ligresti G, Varelas X, Tschumperlin DJ. Jones DL, et al. Among authors: diaz espinosa am. J Cell Biol. 2021 May 3;220(5):e202007152. doi: 10.1083/jcb.202007152. J Cell Biol. 2021. PMID: 33625469 Free PMC article.
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis.
Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ. Haak AJ, et al. Among authors: diaz espinosa am. Sci Transl Med. 2019 Oct 30;11(516):eaau6296. doi: 10.1126/scitranslmed.aau6296. Sci Transl Med. 2019. PMID: 31666402 Free PMC article.
Targeting GPCR Signaling for Idiopathic Pulmonary Fibrosis Therapies.
Haak AJ, Ducharme MT, Diaz Espinosa AM, Tschumperlin DJ. Haak AJ, et al. Among authors: diaz espinosa am. Trends Pharmacol Sci. 2020 Mar;41(3):172-182. doi: 10.1016/j.tips.2019.12.008. Epub 2020 Jan 30. Trends Pharmacol Sci. 2020. PMID: 32008852 Free PMC article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 34005393