Dias LRS - Search Results

1

Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies.

Ribeiro JLS, Soares JCAV, Portapilla GB, Providello MV, Lima CHS, Muri EMF, de Albuquerque S, Dias LRS. Ribeiro JLS, et al. Among authors: dias lrs. Bioorg Med Chem. 2021 Jan 1;29:115855. doi: 10.1016/j.bmc.2020.115855. Epub 2020 Nov 6. Bioorg Med Chem. 2021. PMID: 33199200

2

Synthesis and analgesic properties of 5-acyl-arylhydrazone 1-H pyrazolo [3,4-b] pyridine derivatives.

Dias LR, Alvim MJ, Freitas AC, Barreiro EJ, Miranda AL. Dias LR, et al. Pharm Acta Helv. 1994 Dec;69(3):163-9. doi: 10.1016/0031-6865(94)90019-1. Pharm Acta Helv. 1994. PMID: 7846086

3

Synthesis and biological activity of new potential antimalarial: 1H-pyrazolo[3,4-b]pyridine derivatives.

Dias LR, Freitas AC, Barreiro EJ, Goins DK, Nanayakkara D, McChesney JD. Dias LR, et al. Boll Chim Farm. 2000 Jan-Feb;139(1):14-20. Boll Chim Farm. 2000. PMID: 10829547

4

Synthesis, in vitro evaluation, and SAR studies of a potential antichagasic 1H-pyrazolo[3,4-b]pyridine series.

Dias LR, Santos MB, Albuquerque Sd, Castro HC, de Souza AM, Freitas AC, DiVaio MA, Cabral LM, Rodrigues CR. Dias LR, et al. Bioorg Med Chem. 2007 Jan 1;15(1):211-9. doi: 10.1016/j.bmc.2006.09.067. Epub 2006 Oct 1. Bioorg Med Chem. 2007. PMID: 17064907

5

Synthesis, antichagasic in vitro evaluation, cytotoxicity assays, molecular modeling and SAR/QSAR studies of a 2-phenyl-3-(1-phenyl-1H-pyrazol-4-yl)-acrylic acid benzylidene-carbohydrazide series.

Vera-Divaio MA, Freitas AC, Castro HC, de Albuquerque S, Cabral LM, Rodrigues CR, Albuquerque MG, Martins RC, Henriques MG, Dias LR. Vera-Divaio MA, et al. Bioorg Med Chem. 2009 Jan 1;17(1):295-302. doi: 10.1016/j.bmc.2008.10.085. Epub 2008 Nov 5. Bioorg Med Chem. 2009. PMID: 19036592

6

Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases.

Geraldo RB, Bello ML, Dias LR, Vera MA, Nagashima T, Abreu PA, Santos MB, Albuquerque MG, Cabral LM, Freitas AC, Kalil MV, Rodrigues CR, Castro HC. Geraldo RB, et al. J Atheroscler Thromb. 2010 Jul 30;17(7):730-9. doi: 10.5551/jat.3293. Epub 2010 Jun 2. J Atheroscler Thromb. 2010. PMID: 20523012 Free article.

7

Molecular dynamics simulations of the free and inhibitor-bound cruzain systems in aqueous solvent: insights on the inhibition mechanism in acidic pH.

Hoelz LV, Leal VF, Rodrigues CR, Pascutti PG, Albuquerque MG, Muri EM, Dias LR. Hoelz LV, et al. J Biomol Struct Dyn. 2016 Sep;34(9):1969-78. doi: 10.1080/07391102.2015.1100139. Epub 2015 Nov 26. J Biomol Struct Dyn. 2016. PMID: 26414241

8

Synthesis, biological evaluation and molecular modeling of pseudo-peptides based statine as inhibitors for human tissue kallikrein 5.

Hoelz LVB, Zorzanelli BC, Azevedo PHRA, Passos SG, de Souza LR, Zani M, Pinheiro S, Puzer L, Dias LRS, Muri EMF. Hoelz LVB, et al. Among authors: dias lrs. Eur J Med Chem. 2016 Apr 13;112:39-47. doi: 10.1016/j.ejmech.2016.01.060. Epub 2016 Feb 2. Eur J Med Chem. 2016. PMID: 26874743

9

Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor.

Barros TG, Santos JAN, de Souza BEG, Sodero ACR, de Souza AMT, da Silva DP, Rodrigues CR, Pinheiro S, Dias LRS, Abrahim-Vieira B, Puzer L, Muri EMF. Barros TG, et al. Among authors: dias lrs. Bioorg Med Chem Lett. 2017 Jan 15;27(2):314-318. doi: 10.1016/j.bmcl.2016.11.051. Epub 2016 Nov 18. Bioorg Med Chem Lett. 2017. PMID: 27914800

10

New carbohydrazide derivatives of 1H-pyrazolo[3,4-b]pyridine and trypanocidal activity.

Salvador RR, Bello ML, Barreto IR, Vera MA, Muri EM, Albuquerque S, Dias LR. Salvador RR, et al. An Acad Bras Cienc. 2016 Oct-Dec;88(4):2341-2348. doi: 10.1590/0001-3765201620160087. Epub 2016 Dec 1. An Acad Bras Cienc. 2016. PMID: 27925033 Free article.

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