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Neratinib + fulvestrant + trastuzumab for HR-positive, HER2-negative, HER2-mutant metastatic breast cancer: outcomes and biomarker analysis from the SUMMIT trial.
Ann Oncol. 2023 Oct;34(10):885-898. doi: 10.1016/j.annonc.2023.08.003. Epub 2023 Aug 18.
Ann Oncol. 2023.
PMID: 37597578
Free article.
Clinical Trial.
Pharmacokinetics of neratinib during coadministration with lansoprazole in healthy subjects.
Keyvanjah K, DiPrimeo D, Li A, Obaidi M, Swearingen D, Wong A.
Keyvanjah K, et al. Among authors: diprimeo d.
Br J Clin Pharmacol. 2017 Mar;83(3):554-561. doi: 10.1111/bcp.13132. Epub 2016 Oct 16.
Br J Clin Pharmacol. 2017.
PMID: 27628584
Free PMC article.
Clinical Trial.
Item in Clipboard
Final findings from the CONTROL trial: Strategies to reduce the incidence and severity of neratinib-associated diarrhea in patients with HER2-positive early-stage breast cancer.
Chan A, Ruiz-Borrego M, Marx G, Chien AJ, Rugo HS, Brufsky A, Thirlwell M, Trudeau M, Bose R, García-Sáenz JA, Egle D, Pistilli B, Wassermann J, Cheong KA, Schnappauf B, Semsek D, Singer CF, Foruzan N, DiPrimeo D, McCulloch L, Hurvitz SA, Barcenas CH.
Chan A, et al. Among authors: diprimeo d.
Breast. 2023 Feb;67:94-101. doi: 10.1016/j.breast.2022.12.003. Epub 2022 Dec 14.
Breast. 2023.
PMID: 36702070
Free PMC article.
Item in Clipboard
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers.
Harding JJ, Piha-Paul SA, Shah RH, Murphy JJ, Cleary JM, Shapiro GI, Quinn DI, Braña I, Moreno V, Borad M, Loi S, Spanggaard I, Park H, Ford JM, Arnedos M, Stemmer SM, de la Fouchardiere C, Fountzilas C, Zhang J, DiPrimeo D, Savin C, Duygu Selcuklu S, Berger MF, Eli LD, Meric-Bernstam F, Jhaveri K, Solit DB, Abou-Alfa GK.
Harding JJ, et al. Among authors: diprimeo d.
Nat Commun. 2023 Feb 6;14(1):630. doi: 10.1038/s41467-023-36399-y.
Nat Commun. 2023.
PMID: 36746967
Free PMC article.
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Overall survival with neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): A randomised, double-blind, placebo-controlled, phase 3 trial.
Holmes FA, Moy B, Delaloge S, Chia SKL, Ejlertsen B, Mansi J, Iwata H, Gnant M, Buyse M, Barrios CH, Silovski T, Šeparović R, Bashford A, Zotano AG, Denduluri N, Patt D, Gokmen E, Gore I, Smith JW 2nd, Loibl S, Masuda N, Tomašević Z, Petráková K, DiPrimeo D, Wong A, Martin M, Chan A; ExteNET Study Group.
Holmes FA, et al. Among authors: diprimeo d.
Eur J Cancer. 2023 May;184:48-59. doi: 10.1016/j.ejca.2023.02.002. Epub 2023 Feb 10.
Eur J Cancer. 2023.
PMID: 36898233
Free article.
Clinical Trial.
Item in Clipboard
Targeting HER2-mutant metastatic cervical cancer with neratinib: Final results from the phase 2 SUMMIT basket trial.
Friedman CF, D'Souza A, Bello Roufai D, Tinker AV, de Miguel M, Gambardella V, Goldman J, Loi S, Melisko ME, Oaknin A, Spanggaard I, Shapiro GI, ElNaggar AC, Panni S, Ravichandran V, Frazier AL, DiPrimeo D, Eli LD, Solit DB.
Friedman CF, et al. Among authors: diprimeo d.
Gynecol Oncol. 2024 Feb;181:162-169. doi: 10.1016/j.ygyno.2023.12.004. Epub 2024 Jan 11.
Gynecol Oncol. 2024.
PMID: 38211393
Free article.
Clinical Trial.
Item in Clipboard
Pharmacokinetics and safety of neratinib during co-administration with loperamide in healthy subjects.
Keyvanjah K, Cooke B, Martin D, Di Primeo D, Sterling L, Liang J, Olek E, Rubets I, Wong A.
Keyvanjah K, et al.
Cancer Chemother Pharmacol. 2019 Nov;84(5):1125-1132. doi: 10.1007/s00280-019-03951-x. Epub 2019 Sep 11.
Cancer Chemother Pharmacol. 2019.
PMID: 31512028
Clinical Trial.
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