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Glycogen synthase downregulation rescues the amylopectinosis of murine RBCK1 deficiency.
Nitschke S, Sullivan MA, Mitra S, Marchioni CR, Lee JPY, Smith BH, Ahonen S, Wu J, Chown EE, Wang P, Petković S, Zhao X, DiGiovanni LF, Perri AM, Israelian L, Grossman TR, Kordasiewicz H, Vilaplana F, Iwai K, Nitschke F, Minassian BA. Nitschke S, et al. Among authors: digiovanni lf. Brain. 2022 Jul 29;145(7):2361-2377. doi: 10.1093/brain/awac017. Brain. 2022. PMID: 35084461 Free PMC article.
Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling.
Cabral-Dias R, Lucarelli S, Zak K, Rahmani S, Judge G, Abousawan J, DiGiovanni LF, Vural D, Anderson KE, Sugiyama MG, Genc G, Hong W, Botelho RJ, Fairn GD, Kim PK, Antonescu CN. Cabral-Dias R, et al. Among authors: digiovanni lf. J Cell Biol. 2022 Apr 4;221(4):e201808181. doi: 10.1083/jcb.201808181. Epub 2022 Mar 3. J Cell Biol. 2022. PMID: 35238864 Free PMC article.
Upregulated pexophagy limits the capacity of selective autophagy.
Germain K, So RWL, DiGiovanni LF, Watts JC, Bandsma RHJ, Kim PK. Germain K, et al. Among authors: digiovanni lf. Nat Commun. 2024 Jan 9;15(1):375. doi: 10.1038/s41467-023-44005-4. Nat Commun. 2024. PMID: 38195640 Free PMC article.